Evidence map›Paper›PMID 37652664›Full record

ArticleCold Spring Harbor molecular case studies2023

The importance of escalating molecular diagnostics in patients with low-grade pediatric brain cancer.

Majd Al Assaad, Gunes Gundem, Benjamin Liechty, Andrea Sboner, Juan Medina, Elli Papaemmanuil, Cora N Sternberg, Asher Marks, Mark M Souweidane, Jeffrey P Greenfield and 6 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cold Spring Harbor molecular case studies, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 10 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

Majd Al AssaadDepartment of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York 10065, USA.ORCID 0000-0002-9512-0253
Gunes GundemIsabl, Inc., New York, New York 10065, USA.
Benjamin LiechtyDepartment of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York 10065, USA.ORCID 0000-0001-6485-5604
Andrea SbonerDepartment of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York 10065, USA.ORCID 0000-0001-6915-3070
Juan MedinaIsabl, Inc., New York, New York 10065, USA.
Elli PapaemmanuilIsabl, Inc., New York, New York 10065, USA.
Cora N SternbergEnglander Institute for Precision Medicine, Weill Cornell Medicine, New York, New York 10065, USA.
Asher MarksPediatric Hematology/Oncology, Yale Medicine, New Haven, Connecticut 06520, USA.
Mark M SouweidanePediatric Neurological Surgery, Weill Cornell Medicine, New York, New York 10065, USA.
Jeffrey P GreenfieldPediatric Neurological Surgery, Weill Cornell Medicine, New York, New York 10065, USA.
Ivy TranDepartment of Pathology, NYU Langone Health and School of Medicine, New York, New York 10016, USA.
Matija SnuderlDepartment of Pathology, NYU Langone Health and School of Medicine, New York, New York 10016, USA.ORCID 0000-0003-0752-0917
Olivier ElementoEnglander Institute for Precision Medicine, Weill Cornell Medicine, New York, New York 10065, USA.
Marcin ImielinskiDepartment of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York 10065, USA.
David J PisapiaDepartment of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York 10065, USA; djp2002@med.cornell.edu jmm9018@med.cornell.edu.
Juan Miguel MosqueraDepartment of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York 10065, USA; djp2002@med.cornell.edu jmm9018@med.cornell.edu.
Cornell University · USInstitute for Sustainable Communication · USNYU Langone Health · USYale Cancer Center · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

Pilocytic astrocytomas are the most common pediatric brain tumors, typically presenting as low-grade neoplasms. We report two cases of pilocytic astrocytoma with atypical tumor progression. Case 1 involves a 12-yr-old boy with an unresectable suprasellar tumor, negative for

Indexed as

AstrocytomaBrain NeoplasmsChildHumansMaleMutationPathology, MolecularProto-Oncogene Proteins B-rafProto-Oncogene Proteins B-rafastrocytomagliomaneoplasm of the central nervous systemneoplasm of the nervous system

Identifiers

PMID37652664
PMCPMC10815291
OpenAlexW4386332966

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.