Evidence map›Paper›PMID 37652593›Full record

Trial reportBMJ open2023

Growth and neurodevelopmental outcomes of preterm and low birth weight infants in rural Kenya: a cross-sectional study.

Susanne P Martin-Herz, Phelgona Otieno, Grace M Laanoi, Vincent Moshi, Geofrey Olieng'o Okoth, Nicole Santos, Dilys Walker

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03112018 (Strengthening Intrapartum and Immediate Newborn Care to Reduce Morbidity and Mortality of Preterm Infants in Health Facilities in Migori County, Kenya and Busoga Region, Uganda), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03112018 nacompletednot on this map

Strengthening Intrapartum and Immediate Newborn Care to Reduce Morbidity and Mortality of Preterm Infants in Health Facilities in Migori County, Kenya and Busoga Region, Uganda: an Implementation Science RCT

TypeinterventionalSponsorUniversity of California, San FranciscoRan2016 to 2019Enrolled102,988ConditionsPregnancy Complications, Preterm Labor, PreTerm Birth, StillbirthArmsdata strengthening, modified Safe childbirth checklist - control, modified Safe childbirth checklist - enhanced, PRONTO training, QI cycles
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. [Longitudinal study on catch-up growth in preterm infants with small for gestational age at corrected ages 0-24 months].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Susanne P Martin-Herz *Department of Pediatrics, University of California San Francisco, San Francisco, California, USA Susanne.MartinHerz@ucsf.edu.ORCID 0000-0002-2474-3904
Phelgona Otieno *Center for Clinical Research, Kenya Medical Research Institute, Nairobi, Kenya.
Grace M LaanoiDepartment of Paediatrics and Child Health, Maseno University, Maseno, Kenya.
Vincent MoshiCenter for Clinical Research, Kenya Medical Research Institute, Nairobi, Kenya.
Geofrey Olieng'o OkothCenter for Clinical Research, Kenya Medical Research Institute, Nairobi, Kenya.
Nicole SantosInstitute for Global Health Sciences, University of California San Francisco, San Francisco, California, USA.
Dilys WalkerInstitute for Global Health Sciences, University of California San Francisco, San Francisco, California, USA.
Kenya Medical Research Institute · KEUniversity of California, San Francisco · USMaseno University · KE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveData on long-term outcomes of preterm (PT) and low birth weight (LBW) infants in countries with high rates of neonatal mortality and childhood stunting are limited, especially from community settings. The current study sought to explore growth and neurodevelopmental outcomes of PT/LBW infants from a rural community-based setting of Kenya up to 18 months adjusted age.

designCross-sectional study.

settingMigori County, Kenya.

participantsThree hundred and eighty-two PT/LBW infants (50.2% of those identified as eligible) from a cluster randomised control trial evaluating a package of facility-based intrapartum quality of care interventions for newborn survival consented for follow-up. OUTCOME MEASURES: Caregiver interviews and infant health, growth and neurodevelopmental assessments were completed at 6, 12 or 18 months±2 weeks. Data included sociodemographic information, medical history, growth measurements and neurodevelopmental assessment using the Ten Questions Questionnaire, Malawi Developmental Assessment Tool and Hammersmith Infant Neurological Examination. Analyses were descriptive and univariate regression models. No alterations were made to planned data collection.

resultsThe final sample included 362 PT/LBW infants, of which 56.6% were moderate to late PT infants and 64.4% were LBW. Fewer than 2% of parents identified their child as currently malnourished, but direct measurement revealed higher proportions of stunting and underweight than in national demographic and health survey reports. Overall, 22.7% of caregivers expressed concern about their child's neurodevelopmental status. Neurodevelopmental delays were identified in 8.6% of infants based on one or more standardised tools, and 1.9% showed neurological findings indicative of cerebral palsy.

conclusionsMalnutrition and neurodevelopmental delays are common among PT/LBW infants in this setting. Close monitoring and access to early intervention programmes are needed to help these vulnerable infants thrive. TRIAL REGISTRATION NUMBER: NCT03112018.

Indexed as

MalnutritionRural PopulationChildCross-Sectional StudiesGrowth DisordersHumansInfantInfant, Low Birth WeightInfant MortalityInfant, NewbornKenyaCommunity child healthDevelopmental neurology & neurodisabilityNEONATOLOGY

Identifiers

PMID37652593
PMCPMC10476111
OpenAlexW4386334074

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.