Evidence map›Paper›PMID 37652310›Full record

ArticleToxicology and applied pharmacology2023

Toxic element contaminations of prenatal vitamins.

Zhuo Zhang, Thomas Kluz, Max Costa

Open access · greenAbstract read
In one paragraph

Article in Toxicology and applied pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Zhuo ZhangDivision of Environmental Medicine, Department of Medicine, New York University School of Medicine, 341 East 25(th) Street, New York, NY 10010, United States of America.
Thomas KluzDivision of Environmental Medicine, Department of Medicine, New York University School of Medicine, 341 East 25(th) Street, New York, NY 10010, United States of America.
Max CostaDivision of Environmental Medicine, Department of Medicine, New York University School of Medicine, 341 East 25(th) Street, New York, NY 10010, United States of America. Electronic address: max.costa@nyumc.org.
New York University · US

Funding

Carcinogenesis of Nickel and Epigenetic ControlR01ES005512 · NIEHS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI COSTA, MAX · 1991 to 2011
$5.8M
MEG3 deletion drives lung tumorigenesis due to environmental nickel exposureR01CA229234 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI COSTA, MAX · 2019 to 2024
$2.4M
SATB2 and Nickel CarcingenesisR01ES022935 · NIEHS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI COSTA, MAX · 2014 to 2018
$2.1M
NCI NIH HHS R01 CA229234NIEHS NIH HHS R01 ES005512NIEHS NIH HHS R01 ES022935
6 · The paper itself

Abstract

The detrimental effects of gestational and lactational exposure to adverse chemical agents are gathering increasing attention. In our study, the presence of toxic heavy metals in several prenatal vitamins from six brands available in supermarkets and pharmacies was measured using ICP mass spectrometry. Several toxic heavy metals were detected, some at levels that could have potential toxicity to the fetus and the mother as well. Previous studies have also detected toxic heavy metals in prenatal and other vitamins. One of the reasons for toxic heavy metals in "natural vitamins" sold to consumers is that they are produced from naturally grown material and not synthesized. They are likely exposed to the heavy metals from the ground that they are grown in and there has not been any significant attempt to get rid of them before the vitamin pill was sold to consumers. Thus, this problem is not an isolated issue and regulatory agencies should be dealing more aggressively than they have been doing. In fact, several papers have already been published showing similar findings as we are reporting here. The vitamin pills we analyzed have elevated levels of boron, aluminum, molybdenum, barium, lead, titanium, nickel, arsenic, strontium, and cadmium. The levels of total chromium were also elevated but we did not separately determine Cr(III) and the much more hazardous Cr(VI), because of the tedious procedure required to separate these two forms of Cr.

Indexed as

ArsenicMetals, HeavyCadmiumChromiumVitaminsArsenicCadmiumChromiumMetals, HeavyVitaminsCarcinogenesisHeavy metalsPrenatal vitaminsToxicities

Identifiers

PMID37652310
PMCPMC10874124
OpenAlexW4386242891

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.