Evidence map›Paper›PMID 37652033›Full record

ArticlePhysiological measurement2023

HIRA: Heart Rate Interval based Rapid Alert score to characterize autonomic dysfunction among patients with sepsis-related acute respiratory failure (ARF).

Preethi Krishnan, Milad G Rad, Palak Agarwal, Curtis Marshall, Philip Yang, Sivasubramanium V Bhavani, Andre L Holder, Annette Esper, Rishikesan Kamaleswaran

Open access · hybridAbstract read
In one paragraph

Article in Physiological measurement, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Preethi KrishnanDepartment of Biomedical Engineering, Emory University, Atlanta, GA, Georgia.ORCID 0000-0002-2296-4594
Milad G RadDepartment of Biomedical Informatics, Emory University School of Medicine, Atlanta, GA, Georgia.ORCID 0000-0002-9642-4101
Palak AgarwalDepartment of Biomedical Informatics, Emory University School of Medicine, Atlanta, GA, Georgia.
Curtis MarshallDepartment of Biomedical Informatics, Emory University School of Medicine, Atlanta, GA, Georgia.
Philip YangEmory Critical Care Center, Emory University School of Medicine, Atlanta, GA, Georgia.
Sivasubramanium V BhavaniEmory Critical Care Center, Emory University School of Medicine, Atlanta, GA, Georgia.
Andre L HolderEmory Critical Care Center, Emory University School of Medicine, Atlanta, GA, Georgia.
Annette EsperEmory Critical Care Center, Emory University School of Medicine, Atlanta, GA, Georgia.
Rishikesan KamaleswaranDepartment of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, Georgia.
Emory University · USGeorgia Institute of Technology · US

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
The Emory Training Program in Lung HealthT32HL116271 · NHLBI · EMORY UNIVERSITY · PI BROWN, LOU ANN S, GUIDOT, DAVID MARSHALL · 2013 to 2022
$4.2M
Sepsis Physiomarkers for Appropriate Risk Knowledge of monitored patients in the ICU (SPARK-ICU)R01GM139967 · NIGMS · EMORY UNIVERSITY · PI KAMALESWARAN, RISHIKESAN · 2021 to 2025
$2.8M
Characterizing patients at risk for sepsis through Big Data (Supplement)K23GM137182 · NIGMS · EMORY UNIVERSITY · PI HOLDER, ANDRE L · 2020 to 2023
$907k
Identification of Precision Sepsis Subphenotypes Using Vital Sign TrajectoriesK23GM144867 · NIGMS · EMORY UNIVERSITY · PI BHAVANI, SIVASUBRAMANIUM · 2021 to 2025
$890k
NCATS NIH HHS UL1 TR002378NHLBI NIH HHS T32 HL116271NIGMS NIH HHS K23 GM037182NIGMS NIH HHS K23 GM137182NIGMS NIH HHS K23 GM144867NIGMS NIH HHS R01 GM139967
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Respiratory InsufficiencySepsisCell Cycle ProteinsHeart RateHistone ChaperonesHumansIntensive Care UnitsRetrospective StudiesROC CurveTranscription FactorsCell Cycle ProteinsHIRA protein, humanHistone ChaperonesTranscription Factorsacute respiratory failureheart rate variabilitymachine learningsepsis

Identifiers

PMID37652033
PMCPMC10571460
OpenAlexW4386317502

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.