Evidence map›Paper›PMID 37651360›Full record

ArticlePloS one2023

Epidemiology of syphilis infections among pregnant women in Tanzania: Analysis of the 2020 national representative sentinel surveillance.

Bruno Sunguya, Erick Alexander Mboya, Mucho Mizinduko, Belinda Balandya, Amon Sabasaba, Davis Elias Amani, Doreen Kamori, George Ruhago, Rebecca Mkumbwa, Prosper Faustine and 10 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 6 institutions in 1 country.

Bruno SunguyaMuhimbili University of Health and Allied Sciences, Dar es salaam, Tanzania.
Erick Alexander MboyaMuhimbili University of Health and Allied Sciences, Dar es salaam, Tanzania.ORCID 0000-0002-3279-6256
Mucho MizindukoMuhimbili University of Health and Allied Sciences, Dar es salaam, Tanzania.
Belinda BalandyaMuhimbili University of Health and Allied Sciences, Dar es salaam, Tanzania.
Amon SabasabaMuhimbili University of Health and Allied Sciences, Dar es salaam, Tanzania.
Davis Elias AmaniMuhimbili University of Health and Allied Sciences, Dar es salaam, Tanzania.ORCID 0000-0003-0563-8188
Doreen KamoriMuhimbili University of Health and Allied Sciences, Dar es salaam, Tanzania.ORCID 0000-0001-5162-6554
George RuhagoMuhimbili University of Health and Allied Sciences, Dar es salaam, Tanzania.ORCID 0000-0001-7469-7822
Rebecca MkumbwaMuhimbili University of Health and Allied Sciences, Dar es salaam, Tanzania.
Prosper FaustineMinistry of Health, Dodoma, Tanzania.
Werner MaokolaMinistry of Health, Dodoma, Tanzania.
Veryeh SambuMinistry of Health, Dodoma, Tanzania.
Jeremiah MushiMinistry of Health, Dodoma, Tanzania.
Mukome NyamuhagataMinistry of Health, Dodoma, Tanzania.
Boniphace S JulluSt. Francis University College of Health and Allied Sciences, Morogoro, Tanzania.
Amir JuyaTanzania Field Epidemiology and Laboratory Training Program, Dar es Salaam, Tanzania.
Joan RugemalilaMuhimbili National Hospital, Dar es Salaam, Tanzania.
George MgomellaCentre for Diseases Control, Dar es Salaam, Tanzania.
Sarah AsiimweGlobal Fund, Tanzania Country Team, Tanzania.
Andrea B PembeMuhimbili University of Health and Allied Sciences, Dar es salaam, Tanzania.
Muhimbili University of Health and Allied Sciences · TZMinistry of Health, Community Development, Gender, Elderly and Children · TZCatholic University of Health and Allied Sciences · TZMuhimbili National Hospital · TZUniversity of Dar es Salaam · TZWWF Tanzania · TZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSyphilis has detrimental effects on the health of the mother and that of both fetuses and newborns exposed in utero or at delivery. Understanding its local epidemiology is essential for policies, planning, and implementation of targeted preventive interventions. Using data from the 2020 National Sentinel Surveillance of pregnant women attending antenatal clinics (ANCs) in Tanzania we determined the prevalence and determinants of syphilis among pregnant women in Tanzania mainland. METHODOLOGY: The ANC surveillance was conducted in 159 ANC sites from all 26 regions of Tanzania's mainland from September to December 2020. It included all pregnant women 15 years and above on their first ANC visit in the current pregnancy during the survey period. Counseling for syphilis was done using standard guidelines at the ANC and testing was done using rapid SD Bioline HIV/Syphilis Duo test kits. Analysis was done using both descriptive statistics to determine the prevalence and characteristics of syphilis, whereas, logistic regressions were used to examine the independent association between syphilis and dependent variables.

resultsA total of 38,783 women [median age (Interquartile range (IQR)) = 25 (21-30) years] participated in the surveillance. Of them, 582 (1.4%) tested positive for syphilis. A wide regional variation was observed with the highest burden in Kagera (4.5%) to the lowest burden in Kigoma (0.3%). The odds of syphilis infections were higher among older women and those with no formal education. Compared with primigravids, women with 1-2, those with 3-4 and those with more than four previous pregnancies had 1.8 (aOR = 1.8, 95% CI: 1.2-2.5), 2.1 (aOR = 2.1, 95% CI: 1.4-3.1) and 2.6 (aOR = 2.6, 95% CI: 1.7-3.9) higher odds of syphilis infection respectively.

conclusionSyphilis is still prevalent among pregnant women in Tanzania with a wide regional disparity. Efforts to prevent new infections, screen pregnant women, and treat those infected should be strategized to include all regions and renewed emphasis on regions with high burden, and importantly among women who are multipara, with a low level of education, and advanced age.

Indexed as

Pregnant PeopleSyphilisAgedFemaleHumansInfant, NewbornMothersPregnancySentinel SurveillanceTanzania

Identifiers

PMID37651360
PMCPMC10470872
OpenAlexW4386323711

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.