Evidence map›Paper›PMID 37651174›Full record

ArticleJMIR research protocols2023

Identifying the Characteristics of Responders and Nonresponders in a Behavioral Intervention to Increase Physical Activity Among Patients With Moderate to Severe Asthma: Protocol for a Prospective Pragmatic Study.

Fabiano Francisco de Lima, Adriana Claudia Lunardi, David Halen Araújo Pinheiro, Regina Maria Carvalho-Pinto, Rafael Stelmach, Pedro Giavina-Bianchi, Rosana Câmara Agondi, Celso Rf Carvalho

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in JMIR research protocols, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05159076 (Behavioral Intervention to Increase Physical Activity in Patients with Asthma), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05159076 nacompletednot on this map

Behavioral Intervention to Increase Physical Activity in Patients with Asthma: Identifying the Profile of Responders

TypeinterventionalSponsorUniversity of Sao Paulo General HospitalRan2022 to 2024Enrolled100ConditionsAsthmaArmsBehavioral Intervention to Increase Physical Activity
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Fabiano Francisco de LimaDepartment of Physical Therapy, School of Medicine, University of São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0003-1767-4864
Adriana Claudia LunardiDepartment of Physical Therapy, School of Medicine, University of São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-6133-3816
David Halen Araújo PinheiroDepartment of Physical Therapy, School of Medicine, University of São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-8661-9159
Regina Maria Carvalho-PintoPulmonary Division, Instituto do Coração, School of Medicine, University of São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-6344-2127
Rafael StelmachPulmonary Division, Instituto do Coração, School of Medicine, University of São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-5132-1934
Pedro Giavina-BianchiDepartment of Clinical Immunology and Allergy, School of Medicine, University of São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-1034-7580
Rosana Câmara AgondiDepartment of Clinical Immunology and Allergy, School of Medicine, University of São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-0503-5179
Celso Rf CarvalhoDepartment of Physical Therapy, School of Medicine, University of São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0003-3046-3412
Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious research has suggested that most adults improve their asthma control after a short-term behavioral intervention program to increase physical activity in daily life (PADL). However, the characteristics of individuals who respond and do not respond to this intervention and the medium-term response remain unknown.

objectiveThis study aims to (1) identify the characteristics of adult responders and nonresponders with asthma to a behavioral intervention to increase physical activity and (2) evaluate the functional and clinical benefits in the medium term.

methodsThis prospective pragmatic study will include adults with moderate to severe asthma who enroll in a behavioral intervention. All individuals will receive an educational program and an 8-week intervention to increase PADL (1 time/wk; up to 90 min/session). The educational program will be conducted in a class setting through group discussions and video presentations. Behavioral interventions will be based on the transtheoretical model using counseling, incentives, and individual feedback aiming to increase participation in physical activity. Motivational interviewing and guidelines for overcoming barriers will be used to stimulate individuals to reach their goals. Pre- and postintervention assessments will include the following: PADL (triaxial accelerometry), body composition (octopolar bioimpedance), barriers to PADL (questionnaire), clinical asthma control (Asthma Control Questionnaire), quality of life (Asthma Quality of Life Questionnaire), anxiety and depression levels (Hospital Anxiety and Depression Scale), and exacerbations. "Responders" to the intervention will be defined as those who demonstrate an increase in the number of daily steps (≥2500).

resultsIn December 2021, the clinical trial registration was approved. Recruitment and data collection for the trial is ongoing, and the results of this study are likely to be published in late 2024.

conclusionsThe intervention will likely promote different effects according to the clinical characteristics of the individuals, including asthma control, age, anxiety and depression levels, obesity, and several comorbidities. Identifying individuals who respond or do not respond to behavioral interventions to increase PADL will help clinicians prescribe specific interventions to adults with asthma.

trial registrationClinicalTrials.gov NCT05159076; https://clinicaltrials.gov/ct2/show/NCT05159076. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/49032.

Indexed as

asthmabehavioral interventionphysical activityresponders

Identifiers

PMID37651174
PMCPMC10502597
OpenAlexW4386305691

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.