Evidence map›Paper›PMID 37650948›Full record

ReviewDigestive diseases and sciences2023

Multi-disciplinary Insights from the First European Forum on Visceral Myopathy 2022 Meeting.

Federica Viti, Roberto De Giorgio, Isabella Ceccherini, Arti Ahluwalia, Maria M Alves, Chiara Baldo, Giannina Baldussi, Elena Bonora, Osvaldo Borrelli, Luigi Dall'Oglio and 20 more

Open access · hybridAbstract readReview
In one paragraph

Review in Digestive diseases and sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review of nutrition management of pediatric intestinal pseudo-obstruction.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors at 19 institutions in 7 countries.

Federica VitiInstitute of Biophysics, National Research Council, Via De Marini, 6, 16149, Genoa, Italy. federica.viti@ibf.cnr.it.ORCID http://orcid.org/0000-0002-9651-8896
Roberto De GiorgioDepartment of Translational Medicine, University of Ferrara, Ferrara, Italy.
Isabella CeccheriniIRCCS Istituto Giannina Gaslini Pediatric Hospital, Genoa, Italy.
Arti AhluwaliaCentro di Ricerca 'E. Piaggio' and Department of Information Engineering, University of Pisa, Pisa, Italy.
Maria M AlvesDepartment of Clinical Genetics, Erasmus University Medical Center - Sophia Children's Hospital, Rotterdam, The Netherlands.
Chiara BaldoIRCCS Istituto Giannina Gaslini Pediatric Hospital, Genoa, Italy.
Giannina Baldussi'Uniti per la P.I.P.O.' Patient Advocacy Organization, Brescia, Italy.
Elena BonoraUnit of Medical Genetics, Department of Medical and Surgical Sciences, University of Bologna, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Osvaldo BorrelliDepartment of Gastroenterology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
Luigi Dall'OglioDigestive Surgery and Endoscopy, Bambino Gesù Children's Research Hospital IRCCS, Rome, Italy.
Paolo De CoppiPediatric Surgery, Great Ormond Street Hospital for Children, London, UK.
Carlotta De FilippoInstitute of Agricultural Biology and Biotechnology of the National Research Council, Pisa, Italy.
Pascal de Santa BarbaraPhysiology and Experimental Medicine of the Heart and Muscles (PhyMedExp), University of Montpellier, INSERM, CNRS, Montpellier, France.
Antonella DiamantiBambino Gesù Children's Research Hospital IRCCS, Rome, Italy.
Carlo Di LorenzoDivision of Pediatric Gastroenterology, Hepatology and Nutrition, Nationwide Children's Hospital, Columbus, OH, USA.
Ruggero Di MauloCloud-R, Milan, Italy.
Antonio GaleoneNanotec, National Research Council, Lecce, Italy.
Paolo GandulliaIRCCS Istituto Giannina Gaslini Pediatric Hospital, Genoa, Italy.
Sohaib K HashmiDepartment of Pediatrics, The Children's Hospital of Philadelphia Research Institute and the Perelman School of Medicine at the University of Pennsylvania, Abramson Research Center, Philadelphia, PA, USA.
Florence LacaillePediatric Gastroenterology-Hepatology-Nutrition, Necker-Enfants Malades Hospital, Paris, France.
Laurence Lancon'Association des POIC' Patient Advocacy Organization, Marseille, France.
Salvatore LeoneAMICI ETS, Associazione Nazionale per le Malattie Infiammatorie Croniche dell'Intestino, Milan, Italy.
Maxime M MahéNantes Université, INSERM, TENS, The Enteric Nervous System in Gut and Brain Diseases, IMAD, Nantes, France.
Maria Judit MolnarSemmelweis University, Budapest, Hungary.
Alessandro Palmitelli'POIC e dintorni' Patient Advocacy Organization, Rome, Italy.
Silvia PerinUnit of Pediatric Surgery, Department of Women and Child Health, University of Padua, Padua, Italy.
Alessio Pini PratoUnit of Pediatric Surgery, 'St. Antonio e Biagio e Cesare Arrigo' Hospital, Alessandria, Italy.
Nikhil ThaparStem Cell and Regenerative Medicine, GOS Institute of Child Health, University College London, London, UK.
Massimo VassalliJames Watt School of Engineering, University of Glasgow, Glasgow, UK.
Robert O HeuckerothDepartment of Pediatrics, The Children's Hospital of Philadelphia Research Institute and the Perelman School of Medicine at the University of Pennsylvania, Abramson Research Center, Philadelphia, PA, USA.
Istituto Giannina Gaslini · ITBambino Gesù Children's Hospital · ITChildren's Hospital of Philadelphia · USNational Research Council · ITAzienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo · ITCentre National de la Recherche Scientifique · FRErasmus MC · NLGreat Ormond Street Hospital · GBGreat Ormond Street Hospital for Children NHS Foundation Trust · GBInserm · FRIstituto di Nanotecnologia · ITNationwide Children's Hospital · USQueensland University of Technology · AUSemmelweis University · HUUniversity of Bologna · ITUniversity of Ferrara · ITUniversity of Glasgow · GBUniversity of Padua · ITUniversity of Pisa · IT

Funding

Biochemical and cellular mechanisms linking actin mutations to visceral myopathyR01DK128282 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI HEUCKEROTH, ROBERT O · 2021 to 2025
$3.5M
NIDDK NIH HHS R01 DK128282
6 · The paper itself

Abstract

Visceral myopathy is a rare, life-threatening disease linked to identified genetic mutations in 60% of cases. Mostly due to the dearth of knowledge regarding its pathogenesis, effective treatments are lacking. The disease is most commonly diagnosed in children with recurrent or persistent disabling episodes of functional intestinal obstruction, which can be life threatening, often requiring long-term parenteral or specialized enteral nutritional support. Although these interventions are undisputedly life-saving as they allow affected individuals to avoid malnutrition and related complications, they also seriously compromise their quality of life and can carry the risk of sepsis and thrombosis. Animal models for visceral myopathy, which could be crucial for advancing the scientific knowledge of this condition, are scarce. Clearly, a collaborative network is needed to develop research plans to clarify genotype-phenotype correlations and unravel molecular mechanisms to provide targeted therapeutic strategies. This paper represents a summary report of the first 'European Forum on Visceral Myopathy'. This forum was attended by an international interdisciplinary working group that met to better understand visceral myopathy and foster interaction among scientists actively involved in the field and clinicians who specialize in care of people with visceral myopathy.

Indexed as

Intestinal Pseudo-ObstructionMalnutritionAnimalsChildHumansModels, AnimalMutationQuality of LifeRare DiseasesACTG2Chronic intestinal pseudo-obstruction (CIPO)Gut dysmotilityModels of disease MYH11MYL9MYLK

Identifiers

PMID37650948
PMCPMC10517037
OpenAlexW4386306244

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.