Evidence map›Paper›PMID 37650684›Full record

ArticleInternational health2024

Heterogenous pathogen profile associated with acute conjunctivitis in Nepal.

Meenu Chaudhary, Sanjeeta Sitaula, Kevin Ruder, Cindi Chen, Lina Zhong, Yu Heng Lu, Thomas Abraham, Danny Yu, Armin Hinterwirth, Thomas M Lietman and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Meenu ChaudharyB.P. Koira la Lions Center for Ophthalmic Studies, Institute of Medicine, Tribhuvan University, Kathmandu 44600, Nepal.
Sanjeeta SitaulaB.P. Koira la Lions Center for Ophthalmic Studies, Institute of Medicine, Tribhuvan University, Kathmandu 44600, Nepal.
Kevin RuderF. I. Proctor Foundation, University of California San Francisco, San Francisco, California 94158, USA.
Cindi ChenF. I. Proctor Foundation, University of California San Francisco, San Francisco, California 94158, USA.
Lina ZhongF. I. Proctor Foundation, University of California San Francisco, San Francisco, California 94158, USA.
Yu Heng LuF. I. Proctor Foundation, University of California San Francisco, San Francisco, California 94158, USA.
Thomas AbrahamF. I. Proctor Foundation, University of California San Francisco, San Francisco, California 94158, USA.
Danny YuF. I. Proctor Foundation, University of California San Francisco, San Francisco, California 94158, USA.
Armin HinterwirthF. I. Proctor Foundation, University of California San Francisco, San Francisco, California 94158, USA.
Thomas M LietmanF. I. Proctor Foundation, University of California San Francisco, San Francisco, California 94158, USA.
Thuy DoanF. I. Proctor Foundation, University of California San Francisco, San Francisco, California 94158, USA.
Gerami D SeitzmanF. I. Proctor Foundation, University of California San Francisco, San Francisco, California 94158, USA.ORCID 0000-0003-1791-5509
SCORPIO Study Group
University of California, San Francisco · USTribhuvan University · NP

Funding

UCSF-Proctor Clinician Vision Scholars K12 ProgramK12EY031372 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI THOMAS M LIETMAN, Yvonne Ou · 2020 to 2026
$3.9M
Seasonal Conjunctivitis Outbreak Reporting for Prevention and Improved Outcomes (SCORPIO)R01EY032041 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DOAN, THUY A · 2021 to 2025
$2.0M
NEI NIH HHS K12 EY031372NEI NIH HHS R01 EY032041NIH HHSNIH HHS R01EY032041
6 · The paper itself

Abstract

backgroundInfectious conjunctivitis is common in Nepal. MATERIALS AND

methodsThis prospective study recruited 60 patients with presumed acute infectious conjunctivitis from the B.P. Koirala Lions Center for Ophthalmic Studies in Kathmandu, Nepal. Swabs from the conjunctiva and anterior nares were processed for metagenomic RNA deep sequencing (RNA-seq).

resultsPathogens were identified in 55% of cases. RNA viruses were the most common pathogen class identified. Severe acute respiratory syndrome coronavirus 2 was the most common RNA virus identified.

conclusionsAcute infectious conjunctivitis varies by location. Contrary to expectations, RNA viruses predominated. Repeat surveillance may be useful and RNA-seq allows for detection of the unexpected pathogen including RNA viruses.

Indexed as

SARS-CoV-2Acute DiseaseAdolescentAdultAgedChildChild, PreschoolConjunctivaConjunctivitisCOVID-19FemaleHigh-Throughput Nucleotide SequencingHumansMaleMiddle AgedNepalinfectious conjunctivitisRNA deep-sequencingSCORPIO

Identifiers

PMID37650684
PMCPMC11218877
OpenAlexW4386305439

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.