Evidence map›Paper›PMID 37650625›Full record

ArticlemBio2023

Defining early steps in

Christine A Arbour, Rupa Nagar, Hannah M Bernstein, Soumi Ghosh, Yusra Al-Sammarraie, Helge C Dorfmueller, Michael A J Ferguson, Nicola R Stanley-Wall, Barbara Imperiali

Abstract read
In one paragraph

Article in mBio, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Glycoconjugate diversification inbioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Review
  6. Genetic Characterisation of Closely RelatedInternational journal of molecular sciences · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Christine A Arbour *Department of Biology and Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts, USA.ORCID 0000-0001-6056-296X
Rupa Nagar *Division of Molecular Microbiology, School of Life Sciences, University of Dundee , Dundee, United Kingdom.ORCID 0000-0003-2127-3115
Hannah M BernsteinDepartment of Biology and Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts, USA.ORCID 0000-0003-0871-0376
Soumi GhoshDepartment of Biology and Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts, USA.
Yusra Al-SammarraieDivision of Molecular Microbiology, School of Life Sciences, University of Dundee , Dundee, United Kingdom.
Helge C DorfmuellerDivision of Molecular Microbiology, School of Life Sciences, University of Dundee , Dundee, United Kingdom.ORCID 0000-0003-1288-044X
Michael A J FergusonWellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee , Dundee, United Kingdom.ORCID 0000-0003-1321-8714
Nicola R Stanley-WallDivision of Molecular Microbiology, School of Life Sciences, University of Dundee , Dundee, United Kingdom.ORCID 0000-0002-5936-9721
Barbara ImperialiDepartment of Biology and Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts, USA.ORCID 0000-0002-5749-7869

Funding

SPECIFICITY IN CO- AND POST-TRANSLATIONAL MODIFICATIONR01GM039334 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ALLEN, KAREN N., IMPERIALI, BARBARA · 1993 to 2025
$8.0M
Structure and function of the monotopic phosphoglycosyl transferase superfamily: Initiators of biosynthesis of complex bacterial glycoconjugatesR01GM131627 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ALLEN, KAREN N. · 2019 to 2025
$3.1M
Design and synthesis of nucleoside-based small molecules to inhibit phosphoglycosyl transferasesF32GM136023 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ARBOUR, CHRISTINE · 2020 to 2023
$234k
NIGMS NIH HHS F32 GM136023NIGMS NIH HHS R01 GM039334NIGMS NIH HHS R01 GM131627
6 · The paper itself

Abstract

importanceBiofilms are the communal way of life that microbes adopt to increase survival. Key to our ability to systematically promote or ablate biofilm formation is a detailed understanding of the biofilm matrix macromolecules. Here, we identify the first two essential steps in the

Indexed as

Bacillus subtilisBiofilmsBacterial ProteinsExtracellular Polymeric Substance MatrixBacterial Proteinsbacillosaminebiofilmchemoenzymatic synthesisgenetic complementation

Identifiers

PMID37650625
PMCPMC10653937

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.