Evidence map›Paper›PMID 37650229›Full record

ArticleOral diseases2024

Dental evaluation and clearance prior to allogeneic hematopoietic cell transplantation.

David Dean, Stephanie J Lee, Corey Cutler, Ted A Gooley, Philippe Hujoel, Uhlee Yuri Oh, Lisa Bennett-Johnson, Mary K Hagstrom, Marilynn Rothen, Michele Lloid and 2 more

Open access · greenAbstract read
In one paragraph

Article in Oral diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Impact of health insurance coverage on dentition status prior to hematopoietic cell transplant: A 10-year single-institution observational study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

David DeanUniversity of Washington School of Dentistry, Seattle, Washington, USA.ORCID 0000-0002-9750-6862
Stephanie J LeeClinical Research Division, Fred Cancer Center, Seattle, Washington, USA.
Corey CutlerDana-Farber Cancer Institute, Boston, Massachusetts, USA.
Ted A GooleyClinical Research Division, Fred Cancer Center, Seattle, Washington, USA.
Philippe HujoelUniversity of Washington School of Dentistry, Seattle, Washington, USA.
Uhlee Yuri OhBrigham and Women's Hospital, Boston, Massachusetts, USA.
Lisa Bennett-JohnsonBrigham and Women's Hospital, Boston, Massachusetts, USA.
Mary K HagstromUniversity of Washington School of Dentistry, Seattle, Washington, USA.
Marilynn RothenUniversity of Washington School of Dentistry, Seattle, Washington, USA.
Michele LloidUniversity of Washington School of Dentistry, Seattle, Washington, USA.
Herve SroussiBrigham and Women's Hospital, Boston, Massachusetts, USA.
Nathaniel TreisterDivision of Oral Medicine and Dentistry, Brigham and Women's Hospital, Boston, Massachusetts, USA.
University of Washington · USBrigham and Women's Hospital · USSeattle Cancer Care Alliance · USDana-Farber Cancer Institute · US

Funding

Transform Dissemination and Implementation Science in CTSA ProgramsUL1TR002319 · NCATS · UNIVERSITY OF WASHINGTON · PI John K. Amory · 2017 to 2026
$100.0M
Long Term Oral Health Outcomes in the Chronic GVHD ConsortiumR01DE028336 · NIDCR · BRIGHAM AND WOMEN'S HOSPITAL · PI SROUSSI, HERVE Y, TREISTER, NATHANIEL S · 2019 to 2023
$3.7M
Training and Career Development CoreU54CA163438 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI LEE, STEPHANIE J · 2011 to 2014
$3.7M
NCATS NIH HHSNCATS NIH HHS UL1 TR002319NCI NIH HHS U54 CA163438NIDCR NIH HHSNIDCR NIH HHS R01 DE028336NIH HHS
6 · The paper itself

Abstract

introductionDental examination and stabilization are performed prior to allogeneic hematopoietic cell transplantation to decrease infection risk during neutropenia. Burden of dental disease and treatment need is not well characterized in this population.

objectivesThis report describes the dental status of a cohort of patients within the Chronic Graft-versus-Host Disease Consortium and treatment rendered prior to transplant.

methodsThe cohort included 486 subjects (Fred Hutchinson: n = 245; Dana-Farber: n = 241). Both centers have institutional-based dental clearance programs. Data were retrospectively abstracted from medical records by calibrated oral health specialists.

resultsThe median age at transplant was 55.9 years, 62.1% were male, and 88% were white. Thirteen patients were edentulous (2.7%). The mean teeth among dentate patients before clearance was 26.0 (SD, 4.6). Dental findings included untreated caries (31.2%), restorations (91.6%), endodontically treated teeth (48.1%), and dental implants (5.7%). Pretransplant procedures during clearance included endodontic therapy (3.6%; mean = 0.1 teeth), restorations (25.1%; mean = 0.7), dental prophylaxis (59.2%), scaling/root planing (5.1%), and extraction (13.2%; mean = 0.3). The mean teeth after clearance was 25.6 (SD, 5.0).

conclusionsRetrospective analysis of pre-AlloHCT dental data in subjects at two large transplant centers identified low levels of dental need. Findings suggest high access to care.

Indexed as

Hematopoietic Stem Cell TransplantationAdultAgedDental CariesDental ImplantsDental ProphylaxisDental Restoration, PermanentFemaleGraft vs Host DiseaseHumansMaleMiddle AgedRetrospective StudiesTransplantation, HomologousDental Implantsdental evaluation and managementhematopoietic stem cell transplantimmunosuppressionOral infectionOral medicinesupportive care

Identifiers

PMID37650229
PMCPMC10902180
OpenAlexW4386305777

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.