Evidence map›Paper›PMID 37650112›Full record

ReviewFrontiers in physiology2023

Derivation and elimination of uremic toxins from kidney-gut axis.

Ying Xu, Wen-Di Bi, Yu-Xuan Shi, Xin-Rui Liang, Hai-Yan Wang, Xue-Li Lai, Xiao-Lu Bian, Zhi-Yong Guo

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ying XuDepartment of Nephrology, Changhai Hospital of Naval Medical University, Shanghai, China.
Wen-Di BiBrigade One Team, Basic Medical College, Naval Medical University, Shanghai, China.
Yu-Xuan ShiDepartment of Nephrology, Changhai Hospital of Naval Medical University, Shanghai, China.
Xin-Rui LiangDepartment of Nephrology, Changhai Hospital of Naval Medical University, Shanghai, China.
Hai-Yan WangDepartment of Nephrology, Changhai Hospital of Naval Medical University, Shanghai, China.
Xue-Li LaiDepartment of Nephrology, Changhai Hospital of Naval Medical University, Shanghai, China.
Xiao-Lu BianDepartment of Nephrology, Changhai Hospital of Naval Medical University, Shanghai, China.
Zhi-Yong GuoDepartment of Nephrology, Changhai Hospital of Naval Medical University, Shanghai, China.
Second Military Medical University · CNChanghai Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Uremic toxins are chemicals, organic or inorganic, that accumulate in the body fluids of individuals with acute or chronic kidney disease and impaired renal function. More than 130 uremic solutions are included in the most comprehensive reviews to date by the European Uremic Toxins Work Group, and novel investigations are ongoing to increase this number. Although approaches to remove uremic toxins have emerged, recalcitrant toxins that injure the human body remain a difficult problem. Herein, we review the derivation and elimination of uremic toxins, outline kidney-gut axis function and relative toxin removal methods, and elucidate promising approaches to effectively remove toxins.

Indexed as

derivationeliminationgut microbiomenatural productsuremic toxins

Identifiers

PMID37650112
PMCPMC10464841
OpenAlexW4385877123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.