Evidence map›Paper›PMID 37649381›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2023

Discovery of pyrimidine-tethered benzothiazole derivatives as novel anti-tubercular agents towards multi- and extensively drug resistant

Loah R Hemeda, Mahmoud A El Hassab, Mohamed A Abdelgawad, Eman F Khaleel, Marwa M Abdel-Aziz, Faizah A Binjubair, Sara T Al-Rashood, Wagdy M Eldehna, Mohamed K El-Ashrey

Abstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Loah R HemedaDepartment of Medicinal Chemistry, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.
Mahmoud A El HassabDepartment of Medicinal Chemistry, Faculty of Pharmacy, King Salman International University (KSIU), South Sinai, Egypt.
Mohamed A AbdelgawadDepartment of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia.
Eman F KhaleelDepartment of Medical Physiology, College of Medicine, King Khalid University, Asir, Saudi Arabia.
Marwa M Abdel-AzizThe Regional Center for Mycology & Biotechnology, Al-Azhar University, Cairo, Egypt.
Faizah A BinjubairDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Sara T Al-RashoodDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Wagdy M EldehnaDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.ORCID 0000-0001-6996-4017
Mohamed K El-AshreyDepartment of Medicinal Chemistry, Faculty of Pharmacy, King Salman International University (KSIU), South Sinai, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, new benzothiazole-pyrimidine hybrids (

Indexed as

Mycobacterium tuberculosisAntihypertensive AgentsBenzothiazolesMolecular Docking SimulationPyrimidinesAntihypertensive AgentsBenzothiazolesPyrimidinesanti-mycobacterial activityBenzothiazoleDprE1molecular dockingscreening

Identifiers

PMID37649381
PMCPMC10472891

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.