ArticleJournal of atherosclerosis and thrombosis2024
Calculated Small Dense Low-Density Lipoprotein Cholesterol Level is A Predominant Predictor for New Onset of Ischemic Heart Disease.
Article in Journal of atherosclerosis and thrombosis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 16 citations in OpenAlex.
- Prognostic Significance of the Estimated Small Dense Low-Density Lipoprotein Cholesterol Levels in Predicting the Incidence of Coronary Artery Disease: The Nagahama Study and Shizuoka Kokuho Database Study.Journal of atherosclerosis and thrombosis · 2026Article
- Small Dense Low-density Lipoprotein Cholesterol as a Prognostic Risk Factor in Premature Acute Coronary Syndrome with Multivessel Disease: A Retrospective Cohort Study.Journal of atherosclerosis and thrombosis · 2026Article
- An Apparent Association of Metabolic Dysfunction-Associated Steatotic Liver Disease with High Levels of Estimated Small Dense LDL Cholesterol in a Japanese Population.Journal of atherosclerosis and thrombosis · 2026Article
- Estimation of small dense low-density lipoprotein cholesterol and cardiometabolic multimorbidity risk in middle-aged and elderly Chinese: findings from a nationwide prospective cohort.BMC cardiovascular disorders · 2026Article
- Low-density lipoprotein cholesterol to apolipoprotein B ratio as a predictor of clinical outcomes following percutaneous coronary intervention: a propensity score-matched analysis.Cardiovascular intervention and therapeutics · 2026Article
- Elevated level of estimated small dense LDL cholesterol is independently associated with the development of hypertension, regardless of LDL cholesterol level.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
- Construction of Predictive Models for Cardiovascular Mortality by Machine Learning Approaches in Patients Who Underwent Transcatheter Aortic Valve Implantation.Circulation reports · 2025Article
- Unraveling Novel Subsets of Lymphocytes Involved in Sac Expansion in the Tertiary Lymphoid Structure Within an Abdominal Aortic Aneurysm.Journal of the American Heart Association · 2025Article
- Relationship between plasma atherogenic index and incidence of cardiovascular diseases in Chinese middle-aged and elderly people.Scientific reports · 2025Article
- Clinical significance of small dense low-density lipoprotein cholesterol measurement in type 2 diabetes.Journal of diabetes investigation · 2025Review
- Treatment with pemafibrate ameliorates fatty liver index and atherogenic lipid profiles in Japanese patients with type 2 diabetes mellitus.Frontiers in endocrinology · 2025Article
- Validation of Estimated Small Dense Low-Density Lipoprotein Cholesterol Concentration in a Japanese General Population.Journal of atherosclerosis and thrombosis · 2024Article
- Impact of Pemafibrate Therapy on Reducing Small Dense Low-Density-Lipoprotein-Cholesterol Levels in Patients with Hypertriglyceridemia.Journal of clinical medicine · 2023Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimA high level of directly measured small dense low-density lipoprotein cholesterol (sdLDL-C) is a strong risk factor for ischemic heart disease (IHD). However, it remains unclear whether estimated sdLDL-C level is a predictor for IHD. We investigated the associations of new onset of IHD with levels of total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), non-HDL-C, triglycerides (TG), LDL-C and calculated sdLDL-C by Sampson's equation.
methodsAfter exclusion of subjects with IHD or those with TG ≥ 800 mg/dL, a total of 18,176 subjects (men/women: 11,712/6,464, mean age: 46 years) were recruited among 28,990 Japanese individuals who received annual health checkups.
resultsDuring the 10-year follow-up period, 456 men (3.9%) and 121 women (1.9%) newly developed IHD. Multivariable Cox proportional hazard analyses after adjustment of age, sex, obesity, smoking habit, family history of IHD, estimated glomerular filtration rate, hypertension and diabetes mellitus at baseline showed that the hazard ratio (HR) (1.38 [95% confidence interval: 1.03-1.85]) for new onset of IHD in subjects with the 4
conclusionssdLDL-C level calculated by Sampson's equation is a predominant predictor for the development of IHD in a general Japanese population.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.