Evidence map›Paper›PMID 37647907›Full record

ArticleArquivos de neuro-psiquiatria2023

Definitions, phenomenology, diagnosis, and management of the disorders of laughter and crying in amyotrophic lateral sclerosis (ALS): Consensus from ALS and Motor Neuron Disease Scientific Department of the Brazilian Academy of Neurology.

Francisco de Assis Aquino Gondim, Wladimir Bocca Vieira de Rezende Pinto, Marco Antônio Troccoli Chieia, Carolina da Cunha Correia, Francisco Marcos Bezerra Cunha, Mário Emílio Teixeira Dourado, Marcondes Cavalcante França Júnior, Wilson Marques Júnior, Acary Souza Bulle Oliveira, Cleonisio Leite Rodrigues and 2 more

Open access · goldAbstract readConsensus Statement
In one paragraph

Article in Arquivos de neuro-psiquiatria, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 1 country.

Francisco de Assis Aquino GondimUniversidade Federal do Ceará, Departamento de Clínica Médica, Núcleo de Desenvolvimento e Pesquisa de Medicamentos, Fortaleza CE, Brazil.ORCID 0000-0002-8957-5796
Wladimir Bocca Vieira de Rezende PintoUniversidade Federal de São Paulo, Departamento de Neurologia e Neurocirurgia/Ebserh, Setor de Investigações nas Doenças Neuromusculares, São Paulo SP, Brazil.ORCID 0000-0002-0150-525X
Marco Antônio Troccoli ChieiaUniversidade Federal de São Paulo, Departamento de Neurologia e Neurocirurgia/Ebserh, Setor de Investigações nas Doenças Neuromusculares, São Paulo SP, Brazil.ORCID 0000-0002-6034-4847
Carolina da Cunha CorreiaUniversidade de Pernambuco, Recife PE, Brazil.ORCID 0000-0002-2211-3036
Francisco Marcos Bezerra CunhaUniversidade Federal do Cariri, Barbalha CE, Brazil.ORCID 0000-0002-9842-6573
Mário Emílio Teixeira DouradoUniversidade Federal do Rio Grande do Norte, Departamento de Medicina Integrada, Natal RN, Brazil.ORCID 0000-0002-9462-2294
Marcondes Cavalcante França JúniorUniversidade Estadual de Campinas, Departamento de Neurologia, Campinas SP, Brazil.ORCID 0000-0003-0898-2419
Wilson Marques JúniorUniversidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Neurociências, Ribeirão Preto SP, Brazil.ORCID 0000-0002-4589-2749
Acary Souza Bulle OliveiraUniversidade Federal de São Paulo, Departamento de Neurologia e Neurocirurgia/Ebserh, Setor de Investigações nas Doenças Neuromusculares, São Paulo SP, Brazil.ORCID 0000-0002-6986-4937
Cleonisio Leite RodriguesHospital Geral de Fortaleza, Divisão de Neurologia, Fortaleza CE, Brazil.ORCID 0000-0003-0063-8971
Delson José da SilvaUniversidade Federal de Goiás, Hospital das Clínicas, Unidade de Neurologia e Neurocirurgia/Ebserh, Goiânia GO, Brazil.ORCID 0000-0002-1558-6943
Elza Dias-TostaComissão de Ética da Academia Brasileira de Neurologia, São Paulo SP, Brazil.ORCID 0000-0003-3082-3334
Universidade Federal de São Paulo · BRBrazilian Academy of Sciences · BRHospital Geral de Fortaleza · BRUniversidade de Pernambuco · BRUniversidade de Ribeirão Preto · BRUniversidade Estadual de Campinas (UNICAMP) · BRUniversidade Federal de Goiás · BRUniversidade Federal do Cariri · BRUniversidade Federal do Ceará · BRUniversidade Federal do Rio Grande do Norte · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The spectrum of neuropsychiatric phenomena observed in amyotrophic lateral sclerosis (ALS) is wide and not fully understood. Disorders of laughter and crying stand among the most common manifestations. The aim of this study is to report the results of an educational consensus organized by the Brazilian Academy of Neurology to evaluate the definitions, phenomenology, diagnosis, and management of the disorders of laughter and crying in ALS patients. Twelve members of the Brazilian Academy of Neurology - considered to be experts in the field - were recruited to answer 12 questions about the subject. After exchanging revisions, a first draft was prepared. A face-to-face meeting was held in Fortaleza, Brazil on 9.23.22 to discuss it. The revised version was subsequently emailed to all members of the ALS Scientific Department from the Brazilian Academy of Neurology and the final revised version submitted for publication. The prevalence of pseudobulbar affect/pathological laughter and crying (PBA/PLC) in ALS patients from 15 combined studies and 3906 patients was 27.4% (

Indexed as

Amyotrophic Lateral SclerosisLaughterMotor Neuron DiseaseNeurologyBrazilCryingHumans

Identifiers

PMID37647907
PMCPMC10468253
OpenAlexW4386274178

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.