Evidence map›Paper›PMID 37647627›Full record

ArticleBioinformatics (Oxford, England)2023

RNA 3D structure modeling by fragment assembly with small-angle X-ray scattering restraints.

Grzegorz Chojnowski, Rafał Zaborowski, Marcin Magnus, Sunandan Mukherjee, Janusz M Bujnicki

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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  11. Hierarchical Assembly of Single-Stranded RNA.Journal of chemical theory and computation · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Grzegorz ChojnowskiInternational Institute of Molecular and Cell Biology, Warsaw 02-109, Poland.ORCID 0000-0002-3796-8352
Rafał ZaborowskiInternational Institute of Molecular and Cell Biology, Warsaw 02-109, Poland.
Marcin MagnusReMedy International Research Agenda Unit, IMol Polish Academy of Sciences, Warsaw, Poland.ORCID 0000-0002-5232-2234
Sunandan MukherjeeInternational Institute of Molecular and Cell Biology, Warsaw 02-109, Poland.ORCID 0000-0002-4361-0103
Janusz M BujnickiInternational Institute of Molecular and Cell Biology, Warsaw 02-109, Poland.ORCID 0000-0002-6633-165X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

summaryStructure determination is a key step in the functional characterization of many non-coding RNA molecules. High-resolution RNA 3D structure determination efforts, however, are not keeping up with the pace of discovery of new non-coding RNA sequences. This increases the importance of computational approaches and low-resolution experimental data, such as from the small-angle X-ray scattering experiments. We present RNA Masonry, a computer program and a web service for a fully automated modeling of RNA 3D structures. It assemblies RNA fragments into geometrically plausible models that meet user-provided secondary structure constraints, restraints on tertiary contacts, and small-angle X-ray scattering data. We illustrate the method description with detailed benchmarks and its application to structural studies of viral RNAs with SAXS restraints. AVAILABILITY AND IMPLEMENTATION: The program web server is available at http://iimcb.genesilico.pl/rnamasonry. The source code is available at https://gitlab.com/gchojnowski/rnamasonry.

Indexed as

RNA, UntranslatedRNA, ViralScattering, Small AngleX-Ray DiffractionX-RaysRNA, UntranslatedRNA, Viral

Identifiers

PMID37647627
PMCPMC10474949

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.