ArticleImmunity, inflammation and disease2023
Targetoid-like lesions and chilblain-like erythema manifested on hands and feet: A case of Rowell syndrome from China.
Article in Immunity, inflammation and disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed, 2 citations in OpenAlex.
- Systemic lupus erythematosus associated with erythema multiforme: A rare case report of Rowell's syndrome.Clinical case reports · 2024Article
- Targetoid-like lesions and chilblain-like erythema manifested on hands and feet: A case of Rowell syndrome from China.Immunity, inflammation and disease · 2023Article
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6 authors at 2 institutions in 1 country.
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Abstract
backgroundRowell syndrome (RS) is an uncommon condition characterized by erythema multiforme (EM)-like lesions and lupus erythematosus. It is more common in females, and EM may be the first manifestation of the disease with positive autoantibodies, such as antinuclear antibody (ANA), SSA, SSB and rheumatoid factor. The pathogenesis of RS is unknown and is likely caused by drug induction, ultraviolet exposure and infection.
methodWe describe a case of RS from China which presented as characteristic targetoid-like lesions and chilblain-like erythema on hands and feet. This is a case of RS in a female patient from the inpatient department of dermatology.
resultsA 41-year-old female with systemic lupus erythematosus exhibited chilblain-like erythema and characteristic EM lesions on her extremities. She tested positive for serum ANA (1:320) and anti-double-stranded DNA, as well as other autoantibodies. Systemic glucocorticoids and hydroxychloroquine worked effectively for her.
conclusionThe present case met diagnostic criteria of RS. Notably, there was a co-occurrence of facial butterfly erythema, chilblain-like erythema and EM lesions distributed on the limbs in this case.
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