ArticleEuropean radiology2024
The collateral map: prediction of lesion growth and penumbra after acute anterior circulation ischemic stroke.
Article in European radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed, 14 citations in OpenAlex.
- Case Report: Acute hallucinations and delusions following an argument, attributed to temporal lobe hypoperfusion.Frontiers in psychiatry · 2026Article
- Simultaneous generation of color-coded arteriography, venography, and dynamic angiography: methodology and clinical applications in stroke.La Radiologia medica · 2025Observational
- Multiphase CTA vs. MRA collateral map for predicting functional outcomes after acute ischemic stroke.Neuroradiology · 2025Observational
- The CT collateral map: collateral perfusion estimation and baseline lesion assessment after acute anterior circulation ischemic stroke.La Radiologia medica · 2025Article
- Clinical feasibility of deep learning-driven magnetic resonance angiography collateral map in acute anterior circulation ischemic stroke.Scientific reports · 2025Article
- Deep learning biomarker of chronometric and biological ischemic stroke lesion age from unenhanced CT.NPJ digital medicine · 2024Article
- 3D mobile regression vision transformer for collateral imaging in acute ischemic stroke.International journal of computer assisted radiology and surgery · 2024Article
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13 authors at 6 institutions in 2 countries.
Funding
Abstract
objectivesThis study evaluated the collateral map's ability to predict lesion growth and penumbra after acute anterior circulation ischemic strokes.
methodsThis was a retrospective analysis of selected data from a prospectively collected database. The lesion growth ratio was the ratio of the follow-up lesion volume to the baseline lesion volume on diffusion-weighted imaging (DWI). The time-to-maximum (Tmax)/DWI ratio was the ratio of the baseline Tmax > 6 s volume to the baseline lesion volume. The collateral ratio was the ratio of the hypoperfused lesion volume of the phase_FU (phase with the hypoperfused lesions most approximate to the follow-up DWI lesion) to the hypoperfused lesion volume of the phase_baseline of the collateral map. Multiple logistic regression analyses were conducted to identify independent predictors of lesion growth. The concordance correlation coefficients of Tmax/DWI ratio and collateral ratio for lesion growth ratio were analyzed.
resultsFifty-two patients, including twenty-six males (mean age, 74 years), were included. Intermediate (OR, 1234.5; p < 0.001) and poor collateral perfusion grades (OR, 664.7; p = 0.006) were independently associated with lesion growth. Phase_FUs were immediately preceded phases of the phase_baselines in intermediate or poor collateral perfusion grades. The concordance correlation coefficients of the Tmax/DWI ratio and collateral ratio for the lesion growth ratio were 0.28 (95% CI, 0.17-0.38) and 0.88 (95% CI, 0.82-0.92), respectively.
conclusionPrecise prediction of lesion growth and penumbra can be possible using collateral maps, allowing for personalized application of recanalization treatments. Further studies are needed to generalize the findings of this study. CLINICAL RELEVANCE STATEMENT: Precise prediction of lesion growth and penumbra can be possible using collateral maps, allowing for personalized application of recanalization treatments. KEY POINTS: • Cell viability in cerebral ischemia due to proximal arterial steno-occlusion mainly depends on the collateral circulation. • The collateral map shows salvageable brain extent, which can survive by recanalization treatments after acute anterior circulation ischemic stroke. • Precise estimation of salvageable brain makes it possible to make patient-specific treatment decision.
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