Evidence map›Paper›PMID 37646374›Full record

ArticleJournal of medicinal chemistry2023

Pharmacology and Therapeutic Potential of Benzothiazole Analogues for Cocaine Use Disorder.

Comfort A Boateng, Ashley N Nilson, Rebekah Placide, Mimi L Pham, Franziska M Jakobs, Noelia Boldizsar, Scot McIntosh, Leia S Stallings, Ivana V Korankyi, Shreya Kelshikar and 25 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of medicinal chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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  4. Permeability Benchmarking: Guidelines for ComparingJournal of chemical information and modeling · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors at 4 institutions in 1 country.

Comfort A BoatengDepartment of Basic Pharmaceutical Sciences, Fred Wilson School of Pharmacy, High Point University, One University Parkway, High Point, North Carolina 27268, United States.ORCID 0000-0003-1907-431X
Ashley N NilsonMolecular Neuropharmacology Section, National Institute of Neurological Disorders and Stroke-Intramural Research Program, National Institutes of Health, Bethesda, Maryland 20892, United States.
Rebekah PlacideDepartment of Basic Pharmaceutical Sciences, Fred Wilson School of Pharmacy, High Point University, One University Parkway, High Point, North Carolina 27268, United States.
Mimi L PhamDepartment of Basic Pharmaceutical Sciences, Fred Wilson School of Pharmacy, High Point University, One University Parkway, High Point, North Carolina 27268, United States.
Franziska M JakobsDepartment of Basic Pharmaceutical Sciences, Fred Wilson School of Pharmacy, High Point University, One University Parkway, High Point, North Carolina 27268, United States.ORCID 0000-0003-2861-8868
Noelia BoldizsarMolecular Neuropharmacology Section, National Institute of Neurological Disorders and Stroke-Intramural Research Program, National Institutes of Health, Bethesda, Maryland 20892, United States.ORCID 0000-0003-0299-4697
Scot McIntoshDepartment of Basic Pharmaceutical Sciences, Fred Wilson School of Pharmacy, High Point University, One University Parkway, High Point, North Carolina 27268, United States.
Leia S StallingsDepartment of Basic Pharmaceutical Sciences, Fred Wilson School of Pharmacy, High Point University, One University Parkway, High Point, North Carolina 27268, United States.
Ivana V KorankyiDepartment of Basic Pharmaceutical Sciences, Fred Wilson School of Pharmacy, High Point University, One University Parkway, High Point, North Carolina 27268, United States.
Shreya KelshikarDepartment of Chemistry & Biochemistry, Department of Biological & Biomedical Sciences, College of Science and Mathematics, Rowan University, 201 Mullica Hill Road, Glassboro, New Jersey 08028, United States.
Nisha ShahDepartment of Chemistry & Biochemistry, Department of Biological & Biomedical Sciences, College of Science and Mathematics, Rowan University, 201 Mullica Hill Road, Glassboro, New Jersey 08028, United States.
Diandra PanasisDepartment of Chemistry & Biochemistry, Department of Biological & Biomedical Sciences, College of Science and Mathematics, Rowan University, 201 Mullica Hill Road, Glassboro, New Jersey 08028, United States.
Abigail MuccilliDepartment of Chemistry & Biochemistry, Department of Biological & Biomedical Sciences, College of Science and Mathematics, Rowan University, 201 Mullica Hill Road, Glassboro, New Jersey 08028, United States.
Maria LadikDepartment of Chemistry & Biochemistry, Department of Biological & Biomedical Sciences, College of Science and Mathematics, Rowan University, 201 Mullica Hill Road, Glassboro, New Jersey 08028, United States.
Brianna MaslonkaDepartment of Chemistry & Biochemistry, Department of Biological & Biomedical Sciences, College of Science and Mathematics, Rowan University, 201 Mullica Hill Road, Glassboro, New Jersey 08028, United States.
Connor McBrideDepartment of Chemistry & Biochemistry, Department of Biological & Biomedical Sciences, College of Science and Mathematics, Rowan University, 201 Mullica Hill Road, Glassboro, New Jersey 08028, United States.
Moises Ximello SanchezDepartment of Chemistry & Biochemistry, Department of Biological & Biomedical Sciences, College of Science and Mathematics, Rowan University, 201 Mullica Hill Road, Glassboro, New Jersey 08028, United States.
Ebrar AkcaDepartment of Chemistry & Biochemistry, Department of Biological & Biomedical Sciences, College of Science and Mathematics, Rowan University, 201 Mullica Hill Road, Glassboro, New Jersey 08028, United States.
Mohammad AlkhatibDepartment of Chemistry & Biochemistry, Department of Biological & Biomedical Sciences, College of Science and Mathematics, Rowan University, 201 Mullica Hill Road, Glassboro, New Jersey 08028, United States.
Julianna SaezDepartment of Chemistry & Biochemistry, Department of Biological & Biomedical Sciences, College of Science and Mathematics, Rowan University, 201 Mullica Hill Road, Glassboro, New Jersey 08028, United States.
Catherine NguyenDepartment of Chemistry & Biochemistry, Department of Biological & Biomedical Sciences, College of Science and Mathematics, Rowan University, 201 Mullica Hill Road, Glassboro, New Jersey 08028, United States.
Emily KurtyanDepartment of Chemistry & Biochemistry, Department of Biological & Biomedical Sciences, College of Science and Mathematics, Rowan University, 201 Mullica Hill Road, Glassboro, New Jersey 08028, United States.
Jacquelyn DePierroDepartment of Chemistry & Biochemistry, Department of Biological & Biomedical Sciences, College of Science and Mathematics, Rowan University, 201 Mullica Hill Road, Glassboro, New Jersey 08028, United States.
Raymond CrowthersDepartment of Chemistry & Biochemistry, Department of Biological & Biomedical Sciences, College of Science and Mathematics, Rowan University, 201 Mullica Hill Road, Glassboro, New Jersey 08028, United States.
Dylan BruntDepartment of Chemistry & Biochemistry, Department of Biological & Biomedical Sciences, College of Science and Mathematics, Rowan University, 201 Mullica Hill Road, Glassboro, New Jersey 08028, United States.
Alessandro BonifaziMedicinal Chemistry Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse-Intramural Research Program, National Institutes of Health, 333 Cassell Drive, Baltimore, Maryland 21224, United States.ORCID 0000-0002-7306-0114
Amy Hauck NewmanMedicinal Chemistry Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse-Intramural Research Program, National Institutes of Health, 333 Cassell Drive, Baltimore, Maryland 21224, United States.ORCID 0000-0001-9065-4072
Rana RaisDepartment of Neurology, Johns Hopkins Drug Discovery, The Johns Hopkins University School of Medicine, 855 North Wolfe Street, Baltimore, Maryland 21205, United States.ORCID 0000-0003-4059-2453
Barbara S SlusherDepartment of Neurology, Johns Hopkins Drug Discovery, The Johns Hopkins University School of Medicine, 855 North Wolfe Street, Baltimore, Maryland 21205, United States.ORCID 0000-0001-9814-4157
R Benjamin FreeMolecular Neuropharmacology Section, National Institute of Neurological Disorders and Stroke-Intramural Research Program, National Institutes of Health, Bethesda, Maryland 20892, United States.ORCID 0000-0002-2428-0487
David R SibleyMolecular Neuropharmacology Section, National Institute of Neurological Disorders and Stroke-Intramural Research Program, National Institutes of Health, Bethesda, Maryland 20892, United States.ORCID 0000-0002-0624-962X
Kent D StewartDepartment of Basic Pharmaceutical Sciences, Fred Wilson School of Pharmacy, High Point University, One University Parkway, High Point, North Carolina 27268, United States.
Chun WuDepartment of Chemistry & Biochemistry, Department of Biological & Biomedical Sciences, College of Science and Mathematics, Rowan University, 201 Mullica Hill Road, Glassboro, New Jersey 08028, United States.
Scott E HembyDepartment of Basic Pharmaceutical Sciences, Fred Wilson School of Pharmacy, High Point University, One University Parkway, High Point, North Carolina 27268, United States.ORCID 0000-0002-6987-1133
Thomas M KeckDepartment of Chemistry & Biochemistry, Department of Biological & Biomedical Sciences, College of Science and Mathematics, Rowan University, 201 Mullica Hill Road, Glassboro, New Jersey 08028, United States.ORCID 0000-0003-1845-9373
Rowan University · USHigh Point University · USNational Institutes of Health · USJohns Hopkins University · US

Funding

Molecular And Pharmacological Studies Of Dopamine ReceptorsZIANS002263 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI SIBLEY, DAVID · 2009 to 2025
$37.4M
Molecular &Pharmacological Studies Of Dopamine ReceptorZ01NS002263 · NINDS · NEUROLOGICAL DISORDERS AND STROKE · PI SIBLEY, DAVID R. · 1985 to 2008
$3.1M
Dopamine D2-like Functionally Selective AgonistsZIADA000609 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI NEWMAN, AMY HAUCK · 2016 to 2020
$2.8M
U-Rise at Rowan UniversityT34GM136492 · NIGMS · ROWAN UNIVERSITY · PI KECK, THOMAS MCGOWAN, NUCCI, NATHANIEL V · 2021 to 2025
$2.0M
Low-Efficacy Dopamine D4 Receptor Partial Agonists for Cocaine AddictionR21DA050896 · NIDA · HIGH POINT UNIVERSITY · PI BOATENG, COMFORT AHENKAN, KECK, THOMAS MCGOWAN · 2020 to 2021
$428k
Intramural NIH HHS Z01 NS002263Intramural NIH HHS ZIA DA000609Intramural NIH HHS ZIA NS002263NIDA NIH HHS HHSN271201800023CNIDA NIH HHS R21 DA050896NIGMS NIH HHS T34 GM136492
6 · The paper itself

Abstract

Pharmacological targeting of the dopamine D

Indexed as

CocaineSubstance-Related DisordersAnimalsBenzothiazolesBrainHumansRatsSerotoninBenzothiazolesCocaineSerotonin

Identifiers

PMID37646374
PMCPMC10510399
OpenAlexW4386272479

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.