Evidence map›Paper›PMID 37646309›Full record

ArticleJMIR medical informatics2023

Machine Learning-Enabled Clinical Information Systems Using Fast Healthcare Interoperability Resources Data Standards: Scoping Review.

Jeremy A Balch, Matthew M Ruppert, Tyler J Loftus, Ziyuan Guan, Yuanfang Ren, Gilbert R Upchurch, Tezcan Ozrazgat-Baslanti, Parisa Rashidi, Azra Bihorac

Abstract readScoping Review
In one paragraph

Article in JMIR medical informatics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jeremy A Balch *Department of Surgery, University of Florida Health, Gainesville, FL, United States.ORCID 0000-0002-1826-7884
Matthew M Ruppert *Intelligent Critical Care Center, University of Florida, Gainesville, FL, United States.ORCID 0000-0001-9757-4454
Tyler J LoftusDepartment of Surgery, University of Florida Health, Gainesville, FL, United States.ORCID 0000-0001-5354-443X
Ziyuan GuanIntelligent Critical Care Center, University of Florida, Gainesville, FL, United States.ORCID 0009-0009-4824-6927
Yuanfang RenIntelligent Critical Care Center, University of Florida, Gainesville, FL, United States.ORCID 0000-0002-4716-2408
Gilbert R UpchurchDepartment of Surgery, University of Florida Health, Gainesville, FL, United States.ORCID 0000-0002-4679-8623
Tezcan Ozrazgat-BaslantiIntelligent Critical Care Center, University of Florida, Gainesville, FL, United States.ORCID 0000-0002-1158-9928
Parisa RashidiIntelligent Critical Care Center, University of Florida, Gainesville, FL, United States.ORCID 0000-0003-4530-2048
Azra BihoracIntelligent Critical Care Center, University of Florida, Gainesville, FL, United States.ORCID 0000-0002-5745-2863

Funding

Integrating data, algorithms and clinical reasoning for surgical risk assessmentR01GM110240 · NIGMS · UNIVERSITY OF FLORIDA · PI BIHORAC, AZRA, RASHIDI, PARISA · 2016 to 2025
$5.1M
Molecular Biology in Burns and TraumaT32GM008721 · NIGMS · UNIVERSITY OF FLORIDA · PI Philip A Efron · 1999 to 2026
$5.0M
Intelligent Intensive Care Unit (I2CU): Pervasive Sensing and Artificial Intelligence for Augmented Clinical Decision-makingR01EB029699 · NIBIB · UNIVERSITY OF FLORIDA · PI BIHORAC, AZRA, RASHIDI, PARISA · 2021 to 2024
$2.4M
NIGMS NIH HHS R01 GM110240NIGMS NIH HHS T32 GM008721
6 · The paper itself

Abstract

Background: Machine learning-enabled clinical information systems (ML-CISs) have the potential to drive health care delivery and research. The Fast Healthcare Interoperability Resources (FHIR) data standard has been increasingly applied in developing these systems. However, methods for applying FHIR to ML-CISs are variable. Objective: This study evaluates and compares the functionalities, strengths, and weaknesses of existing systems and proposes guidelines for optimizing future work with ML-CISs. Methods: Embase, PubMed, and Web of Science were searched for articles describing machine learning systems that were used for clinical data analytics or decision support in compliance with FHIR standards. Information regarding each system's functionality, data sources, formats, security, performance, resource requirements, scalability, strengths, and limitations was compared across systems. Results: A total of 39 articles describing FHIR-based ML-CISs were divided into the following three categories according to their primary focus: clinical decision support systems (n=18), data management and analytic platforms (n=10), or auxiliary modules and application programming interfaces (n=11). Model strengths included novel use of cloud systems, Bayesian networks, visualization strategies, and techniques for translating unstructured or free-text data to FHIR frameworks. Many intelligent systems lacked electronic health record interoperability and externally validated evidence of clinical efficacy. Conclusions: Shortcomings in current ML-CISs can be addressed by incorporating modular and interoperable data management, analytic platforms, secure interinstitutional data exchange, and application programming interfaces with adequate scalability to support both real-time and prospective clinical applications that use electronic health record platforms with diverse implementations.

Indexed as

clinical decision support systemclinical informaticsdecision supportFast Healthcare Interoperability ResourcesFHIRinformation systemsinteroperabilityinteroperablemachine learningontologiesontologyreview methodologyreview methodsscoping review

Identifiers

PMID37646309
PMCPMC10468818

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.