Evidence map›Paper›PMID 37646261›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2023

Resistin stimulates PC-3 prostate cancer cell growth through stimulation of SOCS3 and SOCS5 genes.

Chi-Wei Liu, Hsuan-Yu Peng, An-Ci Siao, Yi-Wei Tsuei, Yen-Yue Lin, Shine-Gwo Shiah, Li-Jane Shih, Chien-Chih Yeh, Shih-Wei Lee, Yung-Hsi Kao

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Mechanisms by which obesity regulates inflammation and anti-tumor immunity in cancer.Biochemical and biophysical research communications · 2024
    Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Chi-Wei LiuDepartment of Life Sciences, National Central University, Taoyuan 320.ORCID 0000-0002-8800-7711
Hsuan-Yu PengNational Institute of Cancer Research, National Health Research Institutes, Miaoli 350.
An-Ci SiaoDepartment of Life Sciences, National Central University, Taoyuan 320.
Yi-Wei TsueiDepartment of Emergency Medicine, Taoyuan Armed Forces General Hospital, Taoyuan 325.
Yen-Yue LinDepartment of Life Sciences, National Central University, Taoyuan 320.
Shine-Gwo ShiahNational Institute of Cancer Research, National Health Research Institutes, Miaoli 350.
Li-Jane ShihMedical Laboratory, Taoyuan Armed Forces General Hospital, Taoyuan 325.
Chien-Chih YehDivision of Colon and Rectal Surgery, Department of Surgery, Taoyuan Armed Forces General Hospital, Taoyuan 325.
Shih-Wei LeeDepartment of Internal Medicine, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan 330.
Yung-Hsi KaoDepartment of Life Sciences, National Central University, Taoyuan 320.
National Central University · TWTaoyuan Armed Forces General Hospital · TWMinistry of Health and Welfare · KRNational Health Research Institutes · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resistin and suppressors of cytokine signaling (SOCSs) have been reported to regulate prostate cancer (PCa) cell proliferation and survival, respectively. Whether any of the SOCS molecules mediate the mitogenic effect of resistin on PCa cells is unknown. Using PC-3 human PCa cells, we found that resistin upregulates the expression of

Indexed as

ProstateProstatic NeoplasmsHumansMalePC-3 CellsResistinRNA, MessengerSuppressor of Cytokine Signaling 3 ProteinSuppressor of Cytokine Signaling ProteinsToll-Like Receptor 4ResistinRETN protein, humanRNA, MessengerSOCS3 protein, humanSOCS5 protein, humanSOCS7 protein, humanSuppressor of Cytokine Signaling 3 ProteinSuppressor of Cytokine Signaling ProteinsToll-Like Receptor 4human prostate cancer cellResistinsuppressor of cytokine signaling (SOCS)

Identifiers

PMID37646261
PMCPMC10792425
OpenAlexW4386271896

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.