ArticleJournal of the American Heart Association2023
Prognostic Impact of Mitral Regurgitation Before and After Transcatheter Aortic Valve Replacement in Patients With Severe Low-Flow, Low-Gradient Aortic Stenosis.
Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 20 citations in OpenAlex.
- Mitral Regurgitation after TAVR: Sex Differences and Low-Flow Low-Gradient Aortic Stenosis.JACC. Advances · 2026Article
- Unplanned Mechanical Circulatory Support as Hemodynamic Rescue Worsens Outcomes in Transcatheter Aortic Valve Replacement.Journal of clinical medicine · 2026Article
- Prevalence and prognostic implications of different aetiologies of low flow aortic stenosis.Cardiovascular ultrasound · 2025Article
- Myocardial strain and work in patients with severe aortic stenosis and mitral regurgitation undergoing transcatheter aortic valve implantation.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2025Article
- Multivalvular Disease: A Call for Precision, Sequencing and Shared Learning.JACC. Case reports · 2025Article
- Increase in Aortic Valve Mean Gradients One Day After Transcatheter Aortic Valve Implantation: The Role of Mitral Regurgitation.Cardiology research · 2025Article
- Natural History of Tricuspid Regurgitation After Transcatheter Aortic Valve Implantation.Journal of the American Heart Association · 2025Observational
- Natural History of Mitral Regurgitation After Transcatheter Aortic Valve Implantation.The Annals of thoracic surgery · 2025Observational
- Severe Mitral Regurgitation in Paradoxical Low-Flow, Low-Gradient Severe Aortic Stenosis.Circulation. Cardiovascular imaging · 2025Article
- Incremental prognostic value of computed tomography-determined mitral annular dilatation in patients with severe aortic regurgitation undergoing transcatheter aortic valve replacement: a retrospective cohort study.Quantitative imaging in medicine and surgery · 2025Article
- Functional Mitral Regurgitation Post-Isolated Aortic Valve Replacement.Journal of clinical medicine · 2024Article
- Prevalence and Prognostic Significance of Right Ventricular Dysfunction in Patients With Severe Low-Flow, Low-Gradient Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement.Journal of the American Heart Association · 2024Article
- Transcatheter Mitral Valve Repair With the MitraClip Device for Prior Mitral Valve Repair Failure: Insights From the GIOTTO-FAILS Study.Journal of the American Heart Association · 2024Article
- Mitral Annular Calcification-Related Valvular Disease: A Challenging Entity.Journal of clinical medicine · 2024Review
- Residual Mitral Regurgitation After Transcatheter Aortic Valve Replacement: An Important Target for Intervention.Journal of the American Heart Association · 2023Article
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Authors and funding
12 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background There is little evidence about the prognostic role of mitral regurgitation (MR) in patients with low-flow, low-gradient aortic stenosis undergoing transcatheter aortic valve replacement (TAVR). The aim of this study was to assess the prevalence and outcome implications of MR severity in patients with low-flow, low-gradient aortic stenosis undergoing TAVR, and to evaluate whether MR improvement after TAVR could influence clinical outcome. Methods and Results This study included consecutive patients with low-flow, low-gradient aortic stenosis undergoing TAVR at 2 Italian high-volume centers. The study population was categorized according to the baseline MR severity and to the presence of MR improvement at discharge. The primary outcome was the composite of all-cause death and hospitalization for worsening heart failure up to 1 year. The study included 268 patients; 57 (21%) patients showed MR >2+. Patients with MR >2+ showed a lower 1-year survival free from the primary outcome (
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