Evidence map›Paper›PMID 37646056›Full record

ReviewAdvanced pharmaceutical bulletin2023

Tau Protein Biosensors in the Diagnosis of Neurodegenerative Diseases.

Jafar Sadeghzadeh, Parviz Shahabi, Mehdi Farhoudi, Abbas Ebrahimi-Kalan, Ahmad Mobed, Kourosh Shahpasand

Open access · diamondAbstract readReview
In one paragraph

Review in Advanced pharmaceutical bulletin, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jafar SadeghzadehDepartment of Neurosciences and Cognition, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences,Tabriz, Iran.ORCID https://orcid.org/0000-0002-7632-4162
Parviz ShahabiDepartment of Physiology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID https://orcid.org/0000-0001-5594-5544
Mehdi FarhoudiDepartment of Neurosciences and Cognition, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences,Tabriz, Iran.
Abbas Ebrahimi-KalanNeuroscience Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Ahmad MobedPhysical Medicine and Rehabilitation Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID https://orcid.org/0000-0001-8939-3688
Kourosh ShahpasandDepartment of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology (RI-SCBT), Tehran, Iran.
Tabriz University of Medical Sciences · IRRoyan Institute · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tau protein plays a crucial role in diagnosing neurodegenerative diseases. However, performing an assay to detect tau protein on a nanoscale is a great challenge for early diagnosis of diseases. Enzyme-linked immunosorbent assay (ELISA), western-blotting, and molecular-based methods, e.g., PCR and real-time PCR, are the most widely used methods for detecting tau protein. These methods are subject to certain limitations: the need for advanced equipment, low sensitivity, and specificity, to name a few. With the above said, it is necessary to discover advanced and novel methods for monitoring tau protein. Counted among remarkable approaches adopted by researchers, biosensors can largely eliminate the difficulties and limitations associated with conventional methods. The main objective of the present study is to review the latest biosensors developed to detect the tau protein. Furthermore, the problems and limitations of conventional diagnosis methods were discussed in detail.

Indexed as

BiosensorsClinical diagnosisNeurodegenerative diseaseTau protein

Identifiers

PMID37646056
PMCPMC10460811
OpenAlexW4308413778

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.