ArticleResearch square2023
The microenvironment dictates glycocalyx construction and immune surveillance.
Abstract readPreprint
In one paragraph
Article in Research square, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
25 authors.
Kevin M TharpCenter for Bioengineering and Tissue Regeneration, Department of Surgery, University of California San Francisco, San Francisco, CA 94143, USA.
Sangwoo ParkField of Biophysics, Cornell University, Ithaca, NY 14850, USA.
Greg A TimblinCenter for Bioengineering and Tissue Regeneration, Department of Surgery, University of California San Francisco, San Francisco, CA 94143, USA.
Alicia L RichardsQuantitative Biosciences Institute (QBI) and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA; J. David Gladstone Institutes, San Francisco, CA 94158, USA.
Jordan A BergDepartment of Biochemistry, University of Utah, Salt Lake City, UT 84112, USA.
Nicholas M TwellsDepartment of Chemistry, University of Alberta, Edmonton, Alberta T6G 2G2, Canada.
Nicholas M RileyDepartment of Chemistry, Sarafan ChEM-H, Stanford University, Stanford, CA, USA.
Egan L PeltanDepartment of Chemical and Systems Biology, Stanford University School of Medicine, Stanford CA USA 94305.
D Judy ShonDepartment of Chemistry, Sarafan ChEM-H, Stanford University, Stanford, CA, USA.
Erica StevensonQuantitative Biosciences Institute (QBI) and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA; J. David Gladstone Institutes, San Francisco, CA 94158, USA.
Kimberly TsuiDepartment of Molecular and Cellular Biology and Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA 94597, USA.
Francesco PalombaLaboratory for Fluorescence Dynamics, Department of Biomedical Engineering, University of California, Irvine, California, CA 92697, USA.
Austin E Y T LefebvreCalico Life Sciences, South San Francisco, CA, USA.
Ross W SoensMorgridge Institute for Research, Madison, WI 53715, USA; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.
Nadia M E AyadCenter for Bioengineering and Tissue Regeneration, Department of Surgery, University of California San Francisco, San Francisco, CA 94143, USA.
Johanna Ten Hoeve-ScottUCLA Metabolomics Center, Department of Molecular and Medical Pharmacology, University of California, Los Angeles, CA 90095, USA.
Kevin HealyDepartment of Chemical and Systems Biology, Sarafan ChEM-H and Howard Hughes Medical Institute, Stanford University, Stanford, CA USA 94305.ORCID 0000-0002-8524-3671
Michelle DigmanLaboratory for Fluorescence Dynamics, Department of Biomedical Engineering, University of California, Irvine, California, CA 92697, USA.ORCID 0000-0003-4611-7100
Andrew DillinDepartment of Molecular and Cellular Biology and Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA 94597, USA.
Carolyn R BertozziDepartment of Chemical and Systems Biology, Sarafan ChEM-H and Howard Hughes Medical Institute, Stanford University, Stanford, CA USA 94305.
Danielle L SwaneyQuantitative Biosciences Institute (QBI) and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA; J. David Gladstone Institutes, San Francisco, CA 94158, USA.
Lara K MahalDepartment of Chemistry, University of Alberta, Edmonton, Alberta T6G 2G2, Canada.
Jason R CantorMorgridge Institute for Research, Madison, WI 53715, USA; Department of Biochemistry and Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA.
Matthew J PaszekRobert Frederick Smith School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY 14850, USA.
Valerie M WeaverCenter for Bioengineering and Tissue Regeneration, Department of Surgery, University of California San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0003-4786-6752
Funding
Molecular and Cellular Mechanisms in CancerT32CA108462 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GOGA, ANDREI · 2004 to 2024
$10.4MTissue mechanics reprograms the tissue to malignancy and metastasisR35CA242447 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI VALERIE MARIE WEAVER · 2020 to 2026
$6.6MA physical sciences approach to investigate the role of exosomes in metastatic progressionU01CA250044 · NCI · UNIVERSITY OF PENNSYLVANIA · PI GUO, WEI, RADHAKRISHNAN, RAVI · 2021 to 2025
$3.9MTargeting the Cancer GlycocalyxR01CA227942 · NCI · STANFORD UNIVERSITY · PI Carolyn Bertozzi · 2019 to 2026
$3.6MReorienting the Glioblastoma Microenvironment to Respond to ImmunotherapyR01NS109911 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BARCELLOS-HOFF, MARY HELEN, WEAVER, VALERIE MARIE · 2019 to 2023
$2.9MTension-Stat3-miR-mediated metastasisR01CA192914 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SEEWALDT, VICTORIA L., WEAVER, VALERIE MARIE · 2015 to 2019
$2.9MTissue Tension, RANK and Breast Cancer RiskR01CA222508 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HWANG, E.SHELLEY, WEAVER, VALERIE MARIE · 2018 to 2022
$2.8MWide-field super-resolution spinning disk confocal microscopeS10OD028611 · OD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WITTMANN, TORSTEN · 2020 to 2020
$600kMechanical stress reprograms mitochondrial metabolism to support tumor survival and invasion through the mitochondrial unfolded protein responseF32CA236156 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI THARP, KEVIN · 2019 to 2021
$110kCapturing the Holistic Glycocode through Systems GlycobiologyK99GM147304 · NIGMS · STANFORD UNIVERSITY · PI RILEY, NICHOLAS M · 2022 to 2022
$100kContextualizing Chaotic Metabolic Networks and Their RegulationF99CA253744 · NCI · UNIVERSITY OF UTAH · PI BERG, JORDAN ALEXANDER · 2020 to 2021
$73kNCI NIH HHS F32 CA236156NCI NIH HHS F99 CA253744NCI NIH HHS R01 CA192914NCI NIH HHS R01 CA222508NCI NIH HHS R01 CA227942NCI NIH HHS R35 CA242447NCI NIH HHS T32 CA108462NCI NIH HHS U01 CA250044NIGMS NIH HHS K99 GM147304NIH HHS S10 OD028611NINDS NIH HHS R01 NS109911
Abstract
Efforts to identify anti-cancer therapeutics and understand tumor-immune interactions are built with
Indexed as
blebECMglycoformglycomeglycosylationimmune surveillancelectin arraylectin microarraymechano-metabolicMechanopharmacologymetabolismmicroenvironmentsialic acid
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.