Evidence map›Paper›PMID 37645875›Full record

ArticlebioRxiv : the preprint server for biology2023

The Role of Potassium and Calcium Currents in the Bistable Firing Transition.

Fernando S Borges, Paulo R Protachevicz, Diogo L M Souza, Conrado F Bittencourt, Enrique C Gabrick, Lucas E Bentivoglio, José D Szezech, Antonio M Batista, Iberê L Caldas, Salvador Dura-Bernal and 1 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Fernando S BorgesDepartment of Physiology and Pharmacology, State University of New York Downstate Health Sciences University, Brooklyn, New York, USA.
Paulo R ProtacheviczInstitute of Physics, University of São Paulo, 05508-090 São Paulo, SP, Brazil.
Diogo L M SouzaGraduate Program in Science, State University of Ponta Grossa, 84030-900 Ponta Grossa, PR, Brazil.
Conrado F BittencourtGraduate Program in Science, State University of Ponta Grossa, 84030-900 Ponta Grossa, PR, Brazil.
Enrique C GabrickGraduate Program in Science, State University of Ponta Grossa, 84030-900 Ponta Grossa, PR, Brazil.
Lucas E BentivoglioGraduate Program in Science, State University of Ponta Grossa, 84030-900 Ponta Grossa, PR, Brazil.
José D SzezechGraduate Program in Science, State University of Ponta Grossa, 84030-900 Ponta Grossa, PR, Brazil.
Antonio M BatistaGraduate Program in Science, State University of Ponta Grossa, 84030-900 Ponta Grossa, PR, Brazil.
Iberê L CaldasInstitute of Physics, University of São Paulo, 05508-090 São Paulo, SP, Brazil.
Salvador Dura-BernalDepartment of Physiology and Pharmacology, State University of New York Downstate Health Sciences University, Brooklyn, New York, USA.
Rodrigo F O PenaDepartment of Biological Sciences, Florida Atlantic University, Jupiter, Florida, USA.
Universidade Estadual de Ponta Grossa · BRUniversidade de São Paulo · BRFlorida Atlantic University · USNathan Kline Institute for Psychiatric Research · USState University of New York · US

Funding

Dissemination of a tool for data-driven multiscale modeling of brain circuitsU24EB028998 · NIBIB · SUNY DOWNSTATE MEDICAL CENTER · PI DURA-BERNAL, SALVADOR · 2019 to 2023
$1.6M
NIBIB NIH HHS U24 EB028998
6 · The paper itself

Abstract

Healthy brains display a wide range of firing patterns, from synchronized oscillations during slowwave sleep to desynchronized firing during movement. These physiological activities coexist with periods of pathological hyperactivity in the epileptic brain, where neurons can fire in synchronized bursts. Most cortical neurons are pyramidal regular spiking cells (RS) with frequency adaptation and do not exhibit bursts in current-clamp experiments (

Identifiers

PMID37645875
PMCPMC10462112
OpenAlexW4385951223

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.