Evidence map›Paper›PMID 37645866›Full record

ArticlebioRxiv : the preprint server for biology2023

Specification and survival of post-metamorphic branchiomeric neurons in the hindbrain of a non-vertebrate chordate.

Eduardo D Gigante, Katarzyna M Piekarz, Alexandra Gurgis, Leslie Cohen, Florian Razy-Krajka, Sydney Popsuj, Hussan S Ali, Shruthi Mohana Sundaram, Alberto Stolfi

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Eduardo D GiganteSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, 30332; USA.
Katarzyna M PiekarzSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, 30332; USA.
Alexandra GurgisSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, 30332; USA.
Leslie CohenSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, 30332; USA.
Florian Razy-KrajkaSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, 30332; USA.
Sydney PopsujSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, 30332; USA.
Hussan S AliSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, 30332; USA.
Shruthi Mohana SundaramSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, 30332; USA.
Alberto StolfiSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, 30332; USA.
Georgia Institute of Technology · US

Funding

Specification and maintenance of quiescent progenitor cells set aside for the biphasic life cycle of an invertebrate chordateR01GM143326 · NIGMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI STOLFI, ALBERTO · 2021 to 2024
$1.3M
Dissecting gene regulation of stem cell quiescence in CionaF32GM150234 · NIGMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI GIGANTE, EDUARDO D. · 2023 to 2024
$152k
NIGMS NIH HHS F32 GM150234NIGMS NIH HHS R01 GM143326
6 · The paper itself

Abstract

Tunicates are the sister group to the vertebrates, yet most species have a life cycle split between swimming larva and sedentary adult phases. During metamorphosis, larval neurons are largely replaced by adult-specific ones. Yet the regulatory mechanisms underlying this neural replacement remain largely unknown. Using tissue-specific CRISPR/Cas9-mediated mutagenesis in the tunicate

Identifiers

PMID37645866
PMCPMC10461979
OpenAlexW4381167825

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.