ArticlemedRxiv : the preprint server for health sciences2023
A noninvasive clinical method to measure
Article in medRxiv : the preprint server for health sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03267849 (Lamina Cribrosa Depth Change With Change in Eye Pressure), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Lamina Cribrosa Depth Change With Change in Eye Pressure
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0 citing papers in PubMed, 1 citations in OpenAlex.
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4 authors at 1 institution in 1 country.
Funding
Abstract
Objective: To measure mechanical strain of the lamina cribrosa (LC) after intraocular pressure (IOP) change produced one week after a change in glaucoma medication. Design: Cohort study. Participants: Adult glaucoma patients (23 eyes, 15 patients) prescribed a change in IOP-lowering medication. Intervention: Non-invasive optical coherence tomography (OCT) imaging of the eye. Main Outcomes: Deformation calculated by digital volume correlation of OCT scans of the LC before and after IOP lowering by medication. Results: Among 23 eyes, 17 eyes of 12 persons had IOP lowering ≥ 3 mmHg (reduced IOP group) with tensile anterior-posterior Conclusion: LC mechanical strains can be effectively measured by changes in eye drop medication using OCT and are related to degree of visual function loss in glaucoma. Trial Registration: ClinicalTrials.gov Identifier: NCT03267849.
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