Evidence map›Paper›PMID 37645812›Full record

ArticlebioRxiv : the preprint server for biology2024

Increasing the accuracy of single-molecule data analysis using tMAVEN.

Anjali R Verma, Korak Kumar Ray, Maya Bodick, Colin D Kinz-Thompson, Ruben L Gonzalez

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Anjali R VermaDepartment of Chemistry, Columbia University, New York, NY 10027 USA.ORCID 0000-0001-9297-2955
Korak Kumar RayDepartment of Chemistry, Columbia University, New York, NY 10027 USA.ORCID 0000-0001-5390-698X
Maya BodickDepartment of Chemistry, Columbia University, New York, NY 10027 USA.ORCID 0009-0009-7166-5388
Colin D Kinz-ThompsonDepartment of Chemistry, Rutgers University-Newark, Newark, NJ 07102 USA.ORCID 0000-0002-2636-7893
Ruben L GonzalezDepartment of Chemistry, Columbia University, New York, NY 10027 USA.ORCID 0000-0002-1344-5581

Funding

TRAINING PROGRAM IN MOLECULAR BIOPHYSICST32GM008281 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI PALMER, ARTHUR G · 1988 to 2017
$5.4M
The Structural Dynamics of Translation InitiationR01GM084288 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI GONZALEZ, RUBEN L · 2009 to 2022
$4.4M
The role of collisions in rescuing stalled ribosomes in bacteriaR01GM136960 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI Allen Rowdon Buskirk · 2021 to 2026
$1.9M
The structural dynamics of ribosomal frameshifting and ribosome rescueR01GM137608 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI GONZALEZ, RUBEN L · 2020 to 2023
$1.6M
The mechanism through which mRNA translation enhancer elements drive cap-independent translationR01GM128239 · NIGMS · HUNTER COLLEGE · PI GOSS, DIXIE J · 2019 to 2022
$1.3M
NIGMS NIH HHS R01 GM084288NIGMS NIH HHS R01 GM128239NIGMS NIH HHS R01 GM136960NIGMS NIH HHS R01 GM137608NIGMS NIH HHS T32 GM008281
6 · The paper itself

Abstract

Time-dependent single-molecule experiments contain rich kinetic information about the functional dynamics of biomolecules. A key step in extracting this information is the application of kinetic models, such as hidden Markov models (HMMs), which characterize the molecular mechanism governing the experimental system. Unfortunately, researchers rarely know the physico-chemical details of this molecular mechanism

Identifiers

PMID37645812
PMCPMC10462008

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.