Evidence map›Paper›PMID 37645714›Full record

ArticlebioRxiv : the preprint server for biology2023

Osteocalcin of maternal and embryonic origins synergize to establish homeostasis in offspring.

Danilo Correa Pinto, Isabella Canal Delgado, Haiyang Yang, Alisson Clemenceau, André Corvelo, Giuseppe Narzisi, Rajeeva Musunuri, Julian Meyer Berger, Lauren E Hendricks, Kazuya Tokumura and 7 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 4 countries.

Danilo Correa Pinto
Isabella Canal Delgado
Haiyang Yang
Alisson Clemenceau
André Corvelo
Rajeeva Musunuri
Julian Meyer Berger
Lauren E Hendricks
Kazuya Tokumura
Na Luo
Hongchao Li
Franck Oury
Patricia Ducy
Vijay K Yadav
Xiang Li
Gerard Karsenty
Columbia University · USCenter for Excellence in Brain Science and Intelligence Technology · CNNew York Genome Center · USDélégation Paris 5 · FRGifu Pharmaceutical University · JP

Funding

Regulation of adrenal development and function by the mother's skeletonR01HD107574 · NICHD · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI YADAV, VIJAY K · 2021 to 2025
$1.7M
NICHD NIH HHS R01 HD107574
6 · The paper itself

Abstract

Many physiological functions regulated by osteocalcin are affected in adult offspring of mothers experiencing an unhealthy pregnancy. Furthermore, osteocalcin signaling during gestation influences cognition and adrenal steroidogenesis in adult mice. Together these observations suggest that osteocalcin functions during pregnancy may be a broader determinant of organismal homeostasis in adult mammals than previously thought. To test this hypothesis, we analyzed in unchallenged wildtype and

Identifiers

PMID37645714
PMCPMC10462025
OpenAlexW4385803549

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.