Evidence map›Paper›PMID 37645660›Full record

ArticleProgress in biomedical engineering (Bristol, England)2021

A review of low-cost and portable optical coherence tomography.

Ge Song, Evan T Jelly, Kengyeh K Chu, Wesley Y Kendall, Adam Wax

Open access · hybridAbstract read
In one paragraph

Article in Progress in biomedical engineering (Bristol, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 72 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Label-free viability assessment ofBiomedical optics express · 2026
    Article
  6. Optical coherence tomography in the emergency department setting: a case series.American journal of ophthalmology case reports · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Color-neutral and reversible tissue transparency enables longitudinal deep-tissue imaging in live mice.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. New Directions for Ophthalmic OCT - Handhelds, Surgery, and Robotics.Translational vision science & technology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ge SongDepartment of Biomedical Engineering, Duke University, Durham, NC 27708, United States of America.ORCID 0000-0002-1070-0751
Evan T JellyDepartment of Biomedical Engineering, Duke University, Durham, NC 27708, United States of America.ORCID 0000-0003-4678-9716
Kengyeh K ChuDepartment of Biomedical Engineering, Duke University, Durham, NC 27708, United States of America.
Wesley Y KendallDepartment of Biomedical Engineering, Duke University, Durham, NC 27708, United States of America.
Adam WaxDepartment of Biomedical Engineering, Duke University, Durham, NC 27708, United States of America.ORCID 0000-0002-1827-5112
Duke University · US

Funding

Advanced a/LCI systems for improved clinical utilityR01CA210544 · NCI · DUKE UNIVERSITY · PI SHAHEEN, NICHOLAS J, WAX, ADAM · 2017 to 2021
$2.7M
NCI NIH HHS R01 CA210544
6 · The paper itself

Abstract

Optical coherence tomography (OCT) is a powerful optical imaging technique capable of visualizing the internal structure of biological tissues at near cellular resolution. For years, OCT has been regarded as the standard of care in ophthalmology, acting as an invaluable tool for the assessment of retinal pathology. However, the costly nature of most current commercial OCT systems has limited its general accessibility, especially in low-resource environments. It is therefore timely to review the development of low-cost OCT systems as a route for applying this technology to population-scale disease screening. Low-cost, portable and easy to use OCT systems will be essential to facilitate widespread use at point of care settings while ensuring that they offer the necessary imaging performances needed for clinical detection of retinal pathology. The development of low-cost OCT also offers the potential to enable application in fields outside ophthalmology by lowering the barrier to entry. In this paper, we review the current development and applications of low-cost, portable and handheld OCT in both translational and research settings. Design and cost-reduction techniques are described for general low-cost OCT systems, including considerations regarding spectrometer-based detection, scanning optics, system control, signal processing, and the role of 3D printing technology. Lastly, a review of clinical applications enabled by low-cost OCT is presented, along with a detailed discussion of current limitations and outlook.

Indexed as

low costophthalmologyoptical coherence tomographyportable imaging modality

Identifiers

PMID37645660
PMCPMC10465117
OpenAlexW3160565988

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.