Evidence map›Paper›PMID 37645645›Full record

ArticleAJOG global reports2023

Severe cholestasis-associated coagulopathy diagnosed by routine screening: a case report.

Minhazur R Sarker, Leslie Warren, Chloe Getrajdman, Lauren Ferrara

Open access · goldAbstract readCase Reports
In one paragraph

Article in AJOG global reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Minhazur R SarkerDepartment of Obstetrics, Gynecology, and Reproductive Science, Mount Sinai Health System and Icahn School of Medicine at Mount Sinai, New York, NY.
Leslie WarrenDepartment of Obstetrics, Gynecology, and Reproductive Science, Mount Sinai Health System and Icahn School of Medicine at Mount Sinai, New York, NY.
Chloe GetrajdmanDepartment of Obstetrics, Gynecology, and Reproductive Science, Mount Sinai Health System and Icahn School of Medicine at Mount Sinai, New York, NY.
Lauren FerraraDepartment of Obstetrics, Gynecology, and Reproductive Science, Mount Sinai Health System and Icahn School of Medicine at Mount Sinai, New York, NY.
Mount Sinai Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent case reports suggest an association between severe intrahepatic cholestasis of pregnancy and fat-soluble vitamin deficiencies, including vitamin K deficiency. Screening for coagulopathy and fat-soluble vitamin deficiency has been proposed as a possible strategy to identify pregnancies at additional risk of adverse outcomes and allow for earlier risk-reducing iatrogenic preterm delivery. This report highlights a case of routine screening that resulted in the detection of subclinical coagulopathy that allowed for earlier intervention and delivery of a healthy neonate at 34 weeks of gestation. Further prospective studies are needed to determine the clinical use of routine screening in detecting coagulopathy and fat-soluble vitamin deficiency in cases of severe cholestasis.

Indexed as

bile acidscase reportcholestasisfat-soluble vitaminsliver transplantvitamin K

Identifiers

PMID37645645
PMCPMC10461247
OpenAlexW4378594174

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.