Evidence map›Paper›PMID 37645518›Full record

ArticleFrontiers in cardiovascular medicine2023

Catheter ablation of concomitant atrial fibrillation improves survival of patients undergoing transcatheter edge-to-edge mitral valve repair.

Felix Ausbuettel, Sebastian Barth, Georgios Chatzis, Dieter Fischer, Sebastian Kerber, Julian Mueller, Stephan List, Philipp Halbfass, Thomas Deneke, Holger Nef and 5 more

Abstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Impact of Right Ventricular to Pulmonary Artery Coupling on Survival Following Indirect Mitral Annuloplasty.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Felix AusbuettelDepartment of Cardiology, University Hospital Marburg, Philipps University Marburg, Marburg, Germany.
Sebastian BarthDepartment of Cardiology, Cardiovascular Center Bad Neustadt/Saale, Bad Neustadt an der Saale, Germany.
Georgios ChatzisDepartment of Cardiology, University Hospital Marburg, Philipps University Marburg, Marburg, Germany.
Dieter FischerDepartment of Cardiology, Cardiovascular Center Rotenburg/Fulda, Rotenburg an der Fulda, Germany.
Sebastian KerberDepartment of Cardiology, Cardiovascular Center Bad Neustadt/Saale, Bad Neustadt an der Saale, Germany.
Julian MuellerDepartment of Cardiology, University Hospital Marburg, Philipps University Marburg, Marburg, Germany.
Stephan ListDepartment of Cardiology, University Hospital Oldenburg, Carl von Ossietzky University Oldenburg, Oldenburg, Germany.
Philipp HalbfassDepartment of Cardiology, University Hospital Oldenburg, Carl von Ossietzky University Oldenburg, Oldenburg, Germany.
Thomas DenekeDepartment of Cardiology, Cardiovascular Center Bad Neustadt/Saale, Bad Neustadt an der Saale, Germany.
Holger NefDepartment of Cardiology, Cardiovascular Center Rotenburg/Fulda, Rotenburg an der Fulda, Germany.
Hans-Helge MuellerInstitute for Bioinformatics and Biostatistics, Philipps University Marburg, Marburg, Germany.
Dimitar DivchevDepartment of Cardiology, University Hospital Marburg, Philipps University Marburg, Marburg, Germany.
Bernhard SchiefferDepartment of Cardiology, University Hospital Marburg, Philipps University Marburg, Marburg, Germany.
Ulrich LuesebrinkDepartment of Cardiology, University Hospital Marburg, Philipps University Marburg, Marburg, Germany.
Christian WaechterDepartment of Cardiology, University Hospital Marburg, Philipps University Marburg, Marburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Atrial fibrillation (AF) is the most common concomitant disease in patients undergoing transcatheter edge-to-edge repair (TEER) for mitral regurgitation (MR) and detrimentally affects their outcome. While there is increasing evidence for prognostic improvement and safety of catheter ablation (CA) of AF in the overall cohort of heart failure patients, corresponding data in TEER patients are lacking. Objectives: To investigate the impact of treatment regimens for concomitant AF on survival of TEER patients. Methods: In a multicenter observational cohort study consecutive patients successfully undergoing TEER were analyzed and survival of patients receiving CA of concomitant AF was compared with that of patients on pharmacological AF treatment and with that of patients without a history of AF, using propensity score matching (PSM). Results: A total of 821 patients were analyzed. Of these, 608 (74.1%) had concomitant AF, of whom 48 patients received CA. Patients with CA in AF showed significantly higher 3-year-survival after TEER compared to PSM-patients on pharmacological AF treatment (75.5% [36/48] vs. 49.4% [166/336], Conclusions: CA of AF is superior to pharmacotherapy as it significantly improves the survival of TEER patients in a PSM analysis. CA even offsets the prognostic disadvantage of coexisting AF in TEER patients. Given the growing evidence of prognostic benefits in the overall cohort of HF patients, our data point out the importance of treating concomitant AF and support CA as an essential part of a holistic management of TEER patients.

Indexed as

atrial fibrillationcatheter ablationheart failuremitraclipmitral regurgitationmortalityPASCALpulmonary vein isolation

Identifiers

PMID37645518
PMCPMC10461005

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.