Evidence map›Paper›PMID 37645050›Full record

ArticleArXiv2023

Somatomotor-Visual Resting State Functional Connectivity Increases After Two Years in the UK Biobank Longitudinal Cohort.

Anton Orlichenko, Kuan-Jui Su, Qing Tian, Hui Shen, Hong-Wen Deng, Yu-Ping Wang

Abstract readPreprint
PubMed Full text at PMC
In one paragraph

Article in ArXiv, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Anton OrlichenkoDepartment of Biomedical Engineering, Tulane University, New Orleans, LA 70118.
Kuan-Jui SuCenter for Biomedical Informatics and Genomics, School of Medicine, Tulane University, New Orleans, LA 70118.
Qing TianCenter for Biomedical Informatics and Genomics, School of Medicine, Tulane University, New Orleans, LA 70118.
Hui ShenCenter for Biomedical Informatics and Genomics, School of Medicine, Tulane University, New Orleans, LA 70118.
Hong-Wen DengCenter for Biomedical Informatics and Genomics, School of Medicine, Tulane University, New Orleans, LA 70118.
Yu-Ping WangDepartment of Biomedical Engineering, Tulane University, New Orleans, LA 70118.

Funding

Transcranial Direct Current Stimulation for Treatment of Auditory Verbal HalluciP20GM103472 · NIGMS · THE MIND RESEARCH NETWORK · PI BEDRICK, EDWARD J · 2012 to 2017
$14.3M
Multivariate methods for identifying multitask/multimodal brain imaging biomarkersR01EB006841 · NIBIB · THE MIND RESEARCH NETWORK · PI VINCE D CALHOUN, Sergey Plis · 2007 to 2026
$9.8M
Unified multivariate data-driven solutions for static and dynamic brain connectivityR01EB020407 · NIBIB · THE MIND RESEARCH NETWORK · PI ADALI, TULAY, CALHOUN, VINCE D · 2015 to 2018
$2.7M
Integration of brain imaging with genomic and epigenomic dataR01MH104680 · NIMH · TULANE UNIVERSITY OF LOUISIANA · PI CALHOUN, VINCE D, DENG, HONG-WEN · 2014 to 2017
$2.1M
Integration of fMRI imaging, genomics, network and biological knowledgeR01MH107354 · NIMH · TULANE UNIVERSITY OF LOUISIANA · PI WANG, YU-PING · 2015 to 2018
$1.9M
Integration of multiscale genomic data for comprehensive analysis of complex diseR01GM109068 · NIGMS · TULANE UNIVERSITY OF LOUISIANA · PI WANG, YU-PING · 2014 to 2018
$1.6M
Integration of brain imaging and multi-omics data for improved diagnosis and prediction of mental disordersR56MH124925 · NIMH · TULANE UNIVERSITY OF LOUISIANA · PI WANG, YU-PING · 2021 to 2022
$1.1M
NIBIB NIH HHS R01 EB006841NIBIB NIH HHS R01 EB020407NIGMS NIH HHS P20 GM103472NIGMS NIH HHS R01 GM109068NIMH NIH HHS R01 MH104680NIMH NIH HHS R01 MH107354NIMH NIH HHS R56 MH124925
6 · The paper itself

Abstract

Purpose: Functional magnetic resonance imaging (fMRI) and functional connectivity (FC) have been used to follow aging in both children and older adults. Robust changes have been observed in children, where high connectivity among all brain regions changes to a more modular structure with maturation. In this work, we examine changes in FC in older adults after two years of aging in the UK Biobank longitudinal cohort. Approach: We process data using the Power264 atlas, then test whether FC changes in the 2,722-subject longitudinal cohort are statistically significant using a Bonferroni-corrected t-test. We also compare the ability of Power264 and UKB-provided, ICA-based FC to determine which of a longitudinal scan pair is older. Results: We find a 6.8% average increase in SMT-VIS connectivity from younger to older scan (from Conclusions: We conclude that SMT-VIS connectivity increases in the longitudinal cohort, while resting state FC increases generally with age in the cross-sectional cohort. However, we consider the possibility of a change in resting state scanner task between UKB longitudinal data acquisitions.

Indexed as

agingcross-sectionalfMRIfunctional connectivitylongitudinalUK Biobank

Identifiers

PMID37645050
PMCPMC10462162

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LicenceCC BY-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.