Evidence map›Paper›PMID 37644964›Full record

ArticlePatient preference and adherence2023

Impact of COVID-19 Lockdown on Glycemic, Weight, Blood Pressure Control and Medication Adherence in Patients with Type 2 Diabetes.

Ruth Sim, Chun Wie Chong, Navin Kumar Loganadan, Zanariah Hussein, Noor Lita Adam, Shaun Wen Huey Lee

Abstract read
In one paragraph

Article in Patient preference and adherence, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Hypertension in Adults With Diabetes in Southeast Asia: A Systematic Review.Journal of clinical hypertension (Greenwich, Conn.) · 2025
    Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ruth SimSchool of Pharmacy, Monash University Malaysia, Subang Jaya, Selangor, Malaysia.ORCID 0000-0002-5667-9521
Chun Wie ChongSchool of Pharmacy, Monash University Malaysia, Subang Jaya, Selangor, Malaysia.ORCID 0000-0002-6881-8883
Navin Kumar LoganadanDepartment of Pharmacy, Putrajaya Hospital, Ministry of Health Malaysia, Putrajaya, Malaysia.ORCID 0000-0001-6875-8537
Zanariah HusseinDepartment of Medicine, Putrajaya Hospital, Ministry of Health Malaysia, Putrajaya, Malaysia.ORCID 0000-0003-0217-3282
Noor Lita AdamDepartment of Medicine, Hospital Tuanku Jaafar, Ministry of Health Malaysia, Seremban, Negeri Sembilan, Malaysia.
Shaun Wen Huey LeeSchool of Pharmacy, Monash University Malaysia, Subang Jaya, Selangor, Malaysia.ORCID 0000-0001-7361-6576

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medication adherence profoundly affects blood glucose management in patients with type 2 diabetes. Measures to contain the COVID-19 pandemic have affected disease management and medication adherence, owing to limited access to healthcare facilities. This study aimed to examine the impact of the COVID-19 lockdown on adherence to glucose-lowering and lipid-lowering therapies (statins), and glycemic, weight, and systolic blood pressure control measures. A retrospective chart review was conducted one year pre- and post- March 18, 2020, for patients receiving glucose-lowering medications and lipid-lowering therapies (statins) in two major public hospitals in Malaysia. We compared the proportion of days covered by medication, HbA1c level, weight, and systolic blood pressure (SBP) values pre- and after the index date. A total of 1985 patients were included in this study. The adherence rate significantly increased for metformin, sulfonylureas dipeptidyl peptidase 4 inhibitors (DPP4i) and statin after the index date (metformin (PDC: 0.985 vs 0.978, p < 0.001), sulfonylureas (PDC: 0.988 vs 0.979, p < 0.01), DPP4i (PDC: 0.987 vs 0.98, p < 0.001), and statins (PDC: 0.983 vs 0.978, p < 0.05)). HbA1c levels were significantly reduced after the index follow-up (Mean difference: -0.43%, p < 0.001), while there was a 2.5 mmHg (p = 0.03) significant increase in SBP post-index follow-up. No significant changes in weight were observed during the post-index follow-up period. In this study, we observed better medication adherence and glycemic control among patients during the lockdown, but not for weight and systolic blood pressure control.

Indexed as

adherencecovid-19diabetesglycemicSARS-CoV 2weight

Identifiers

PMID37644964
PMCPMC10461747

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.