Evidence map›Paper›PMID 37644584›Full record

ArticleParasites & vectors2023

Semiochemical delivery systems based on natural polymers to attract sand flies (Diptera: Psychodidae).

Ana Carolina Bueno, Vicente Estevam Machado, Flávia Benini da Rocha Silva, Fernanda Isadora Boni, Beatriz Stringhetti Ferreira Cury, Maria Palmira Daflon Gremião, Mara Cristina Pinto

Abstract read
In one paragraph

Article in Parasites & vectors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ana Carolina BuenoDepartment of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Rodovia Araraquara-Jaú, km 1, Araraquara, São Paulo, 14800-903, Brazil.
Vicente Estevam MachadoDepartment of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Rodovia Araraquara-Jaú, km 1, Araraquara, São Paulo, 14800-903, Brazil.
Flávia Benini da Rocha SilvaDepartment of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Rodovia Araraquara-Jaú, km 1, Araraquara, São Paulo, 14800-903, Brazil.
Fernanda Isadora BoniDepartment of Drugs and Medicines, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Rodovia Araraquara-Jaú, km 1, Araraquara, São Paulo, 14800-903, Brazil.
Beatriz Stringhetti Ferreira CuryDepartment of Drugs and Medicines, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Rodovia Araraquara-Jaú, km 1, Araraquara, São Paulo, 14800-903, Brazil.
Maria Palmira Daflon GremiãoDepartment of Drugs and Medicines, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Rodovia Araraquara-Jaú, km 1, Araraquara, São Paulo, 14800-903, Brazil.
Mara Cristina PintoDepartment of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Rodovia Araraquara-Jaú, km 1, Araraquara, São Paulo, 14800-903, Brazil. mara.pinto@unesp.br.

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Financial Code 001International Foundation of Science F-4587
6 · The paper itself

Abstract

backgroundThe successful use of semiochemicals to attract insects to traps is based on research on the most suitable compounds and their release profiles over time. Based on the group's promising results, matrices with a more adequate release profile and more eco-friendly properties for the release of 1-hexanol were developed. To use a more suitable prototype in the field, the most promising systems were added to a capsule and evaluated in a wind tunnel. Behavioral experiments were performed using the sand fly species, Lutzomyia longipalpis, to evaluate the efficacy of the proposed system.

methodsDifferent delivery systems were developed by varying the polymer (gellan gum and pectin) ratio, crosslinker (aluminum chloride) concentration, and glutaraldehyde removal.The delivery systems were loaded with 1-hexanol, and their release profiles were evaluated using gravimetric analysis under ambient and high-humidity conditions. When the matrix system was placed inside a plastic container, modulations in the active release profile were observed and the system could be reused. Actid attraction behaviors of the sand fly species, Lu. longipalpis, were evaluated in a wind tunnel when exposed to 1-hexanol-loaded release systems at different times.

resultsAmong the four formulations evaluated, System 2 (gellan gum and pectin in a 1:1 ratio with 5% aluminum chloride) exhibited the most promising release profile, with greater uniformity and longer compound release time. The maximum 1-hexanol release uniformity was achieved over a longer time, mainly every 24 h, under both ambient and high-humidity conditions. System 2 can be reused at least once with the same structure. The wind tunnel trials exhibited efficient activation and attraction of Lu. longipalpis to 1-hexanol after 24, 48, and 72 h in System 2 placed inside the capsules.

conclusionsThe polymeric matrix supplemented with 1-hexanol and introduced in plastic capsules showed promising results in attracting sand flies. This system can be used as a solution for other attractive compounds as well as in other applications where their release needs to be controlled or prolonged.

Indexed as

PhlebotomusPsychodidaeAluminum ChlorideAnimalsCapsulesHexanolsPectinsPlasticsPolymers1-hexanolAluminum ChlorideCapsulesHexanolsPectinsPlasticsPolymers1-hexanolAttractivenessKairomonesLutzomyia longipalpisRelease systems

Identifiers

PMID37644584
PMCPMC10464299

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.