Evidence map›Paper›PMID 37644523›Full record

ArticleVeterinary research2023

EspE3 plays a role in the pathogenicity of avian pathogenic Escherichia coli.

Qianwen Li, Zhao Qi, Dandan Fu, Bo Tang, Xiangjun Song, Ying Shao, Jian Tu, Kezong Qi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinary research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Qianwen LiAnhui Province Key Laboratory of Veterinary and Disease Control, College of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, China. 1061114200@qq.com.ORCID http://orcid.org/0009-0009-8483-6318
Zhao QiAnhui Province Key Laboratory of Veterinary and Disease Control, College of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, China.
Dandan FuAnhui Province Key Laboratory of Veterinary and Disease Control, College of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, China.
Bo TangInstitute of Veterinary Immunology & Engineering, Jiangsu Academy of Agricultural Sciences, Nanjing, China.
Xiangjun SongAnhui Province Key Laboratory of Veterinary and Disease Control, College of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, China.
Ying ShaoAnhui Province Key Laboratory of Veterinary and Disease Control, College of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, China.
Jian TuAnhui Province Key Laboratory of Veterinary and Disease Control, College of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, China.
Kezong QiAnhui Province Key Laboratory of Veterinary and Disease Control, College of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, China. qkz@ahau.edu.cn.
Anhui Agricultural University · CNJiangsu Academy of Agricultural Sciences · CN

Funding

National Natural Science Foundation of China 31772707National Natural Science Foundation of China 31972644
6 · The paper itself

Abstract

APEC encodes multiple virulence factors that have complex pathogenic mechanisms. In this study, we report a virulence factor named EspE3, which can be secreted from APEC. This protein was predicted to have a leucine-rich repeat domain (LRR) and may have a similar function to IpaH class effectors of the type III secretion system (T3SS). For further exploration, the regulatory correlation between the espE3 and ETT2 genes in APEC was analysed. We then assessed the pathogenicity of EspE3, detected it in APEC secretion proteins and screened the proteins of EspE3 that interact with chicken trachea epithelial cells. This study provides data on a new virulence factor for further exploring the pathogenic mechanism of APEC.

Indexed as

ChickensVirulence FactorsAnimalsBiological TransportEscherichia coliVirulenceVirulence FactorsAPECeffectorEspE3ETT2pathogenicity

Identifiers

PMID37644523
PMCPMC10463865
OpenAlexW4386251609

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.