ArticleAging clinical and experimental research2023
The risk of malnutrition and its clinical implications in older patients with cancer.
Article in Aging clinical and experimental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 6 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 6 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Prevalence of malnutrition and nutritional risk, and associated factors in adults with head and neck cancer: a systematic review and meta-analysis.Frontiers in oncology · 2026Pooled it
- The bidirectional association of malnutrition with depression and anxiety in patients with cancer: a systematic review and meta-analysis of evidence.Aging clinical and experimental research · 2025Pooled it
- Falls among geriatric cancer patients: a systematic review and meta-analysis of prevalence and risk across cancer types.BMC geriatrics · 2025Pooled it
- Risk prediction models for malnutrition in cancer patients: a systematic review and meta-analysis.Frontiers in nutrition · 2025Pooled it
- Association between prognostic nutritional index and survival of patients with oral cancer: a meta-analysis.Frontiers in oncology · 2025Pooled it
- Blood lipid metabolic biomarkers are emerging as significant prognostic indicators for survival in cancer patients.BMC cancer · 2024Pooled it
- Assessment of sleep in older people within comprehensive geriatric assessments: a scoping review.Age and ageing · 2026Article
- Association between oral health and frailty among older cancer patients: a cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Malnutrition in older adults with cancer undergoing outpatient care: associated factors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Machine Learning and Abdominal Aortic Aneurysm: A New Paradigm in Prediction and Prognosis after Endovascular Aneurysm Repair.Annals of vascular diseases · 2026Review
- Associations between masseter and temporal muscle measurements and sarcopenia and nutritional status in older adults.Radiologie (Heidelberg, Germany) · 2025Article
- Machine learning and the nomogram as the accurate tools for predicting postoperative malnutrition risk in esophageal cancer patients.Frontiers in nutrition · 2025Article
- The Aging Stomach: Clinical Implications ofInternational journal of molecular sciences · 2024Review
- Malnutrition and Fall Risk in Older Adults: A Comprehensive Assessment Across Different Living Situations.Nutrients · 2024Article
- Associations of nutrition impact symptoms with depression in patients with advanced cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- The prevalence and co-existence of geriatric syndromes in older patients with dementia compared to those without dementia.Aging clinical and experimental research · 2024Article
- Prevalence and co-incidence of geriatric syndromes according to the ECOG performance status in older cancer patients.Frontiers in medicine · 2024Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimMalnutrition is a common geriatric syndrome with multiple negative outcomes including mortality. However, there is a scarcity of literature that focuses on the relationship between malnutrition risk and its clinical implications on geriatric syndromes and mortality among cancer patients. The aim of this study is to determine the clinical importance of malnutrition risk in geriatric oncology practice.
method180 patients with cancer who were ≥ 65 years were included in the study. All patients were questioned in terms of geriatric syndromes, including polypharmacy, frailty, probable sarcopenia, fall risk, dynapenia, depression, cognitive impairment, insomnia, and excessive daytime sleepiness. Mini Nutritional Assessment scores > 23.5 and 17-23.5 were categorized as well-nourished and malnutrition risk, respectively.
resultsOf the 180 patients (mean age 73.0 ± 5.6 years, female: 50%), the prevalence of malnutrition risk was 28.9%. There was no statistically significant difference between the groups in terms of age, gender, education, marital status, body mass index, and comorbidities except for chronic obstructive pulmonary disease (p > 0.05). After adjustment for age, sex, and body mass index; polypharmacy (odds ratio [OR]: 3.17; 95% confidence interval [CI], 1.48-6.81), reduced calf circumference (OR: 3.72; 95% CI, 1.22-11.38), fall risk (OR: 2.72; 95% CI, 1.03-7.23), depression (OR: 6.24; 95% CI, 2.75-14.18), insomnia (OR: 4.89; 95% CI, 2.16-11.05), and frailty (OR: 2.44; 95% CI, 1.75-3.40) were associated with malnutrition risk compared to well-nourished patients (p < 0.05). Median survival in patients with malnutrition risk was 21.3 months (range 14.1-28.4 95% CI) and median survival in patients who were defined as well nourished was not reached (p < 0.001).
conclusionThe risk of malnutrition was associated with a higher risk for all-cause mortality in older patients with cancer, and was associated with many geriatric syndromes, including polypharmacy, fall risk, frailty, insomnia, and depression.
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