SynthesisVeterinary research communications2024
Protective effects of feed additives on broiler chickens exposed to aflatoxins-contaminated feed: a systematic review and meta-analysis.
Synthesis in Veterinary research communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 15 citations in OpenAlex.
- Can black soldier fly larvae (Hermetia illucens) be utilized by ruminants? a meta-analysis of performance, digestibility, and rumen fermentation responses.BMC veterinary research · 2026Pooled it
- Influence of saponin extracts on enteric methane emission and rumen fermentation: a meta-analysis of in vitro experiments.BMC veterinary research · 2026Pooled it
- Pooled it
- Multicomponent mineral-phytogenic supplementation reduces Ascaridia galli shedding and systemic mycotoxin biomarkers while improving health and productive performance in laying hens.Veterinary world · 2026Article
- Mitigation of aflatoxin B1-induced toxicopathology and immunosuppression in broilers using a multimodal antioxidant formulation.Mycotoxin research · 2026Article
- Mechanisms of AFB1-induced neurotoxicity and protective effect of baicalin via inflammatory and antioxidant pathways in ducklings.Poultry science · 2026Article
- One Health perspective on mycotoxins in poultry production: Ecology, toxicological effects, occupational and environmental exposure, food safety risks, and mitigation strategies (2020-2025).Veterinary world · 2026Review
- Efficacy of a Commercial Mycotoxin Adsorbent Against Low-Level AflatoxinVeterinary medicine international · 2026Article
- Cross-Sectional Survey of Aflatoxin B1 Contamination in Poultry Feeds and Feed Ingredients From Bogor and Bekasi Regencies, West Java, Indonesia.Veterinary medicine international · 2026Article
- Essential oils alleviate coccidiosis impact in broiler chickens: a meta-analysis.Animal bioscience · 2025Article
- The Effect of Clay- and Yeast-Based Mycotoxin Binder on Performance, Lymphoid Organs, Blood Parameters, Immune Response and Haematology Parameters of Broilers Exposed to Aflatoxin BVeterinary medicine and science · 2025Article
- Mitigation of mycotoxin residues and activation of endogenous stem cells in broiler chickens using a toxin binder: Implications for meat safety and performance enhancement.Veterinary world · 2025Article
- Effectiveness of Hydrated Sodium Calcium Aluminosilicates and Discarded Date Pits as Dietary Adsorbents for Aflatoxin B1 in Enhancing Broiler Chicken Productive Performance, Hepatic Function, and Intestinal Health.Animals : an open access journal from MDPI · 2024Article
- Mycotoxin binder for immune and intestinal histopathology ameliorations against Newcastle disease in vaccinated broilers.F1000Research · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 9 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aflatoxin contamination in feed is a common problem in broiler chickens. The present systematic review and meta-analysis examined the impact of aflatoxin-contaminated feed and the efficacy of various feed additives on the production performance of broiler chickens fed aflatoxin-contaminated feed (AF-feed). A total of 35 studies comprising 53 AF-feed experiments were selected following PRISMA guidelines. Feed additives included in the analyses were toxins binder (TB), mannan-oligosaccharides (MOS), organic acid (OA), probiotics (PRO), protein supplementation (PROT), phytobiotics (PHY), and additive mixture (MIX). Random effects model and a frequentist network meta-analysis (NMA) were performed to rank the efficacy of feed additives, reported as standardized means difference (SMD) at 95% confidence intervals (95% CI). Overall, broiler chickens fed AF-feed had significantly lower final body weight (BW) (SMD = 198; 95% CI = 198 to 238) and higher feed conversion ratio (SMD = 0.17; 95% CI = 0.13 to 0.21) than control. Treatments with TB, MOS, and PHY improved the BW of birds fed AF-feed (P < 0.05) to be comparable with non-contaminated feed or control. Predictions on final BW from the broiler-fed aflatoxin-contaminated diet were 15% lower than the control diet. Including feed additives in the aflatoxins diet could ameliorate the depressive effect. Remarkably, our network meta-analysis highlighted that TB was the highest-performing additive (P-score = 0.797) to remedy aflatoxicosis. Altogether, several additives, especially TB, are promising to ameliorate aflatoxicosis in broiler chickens, although the efficacy was low regarding the severity of the aflatoxicosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.