Evidence map›Paper›PMID 37644173›Full record

ArticleMolecular psychiatry2023

Prenatal exposure to common plasticizers: a longitudinal study on phthalates, brain volumetric measures, and IQ in youth.

Akhgar Ghassabian, Michiel van den Dries, Leonardo Trasande, Sander Lamballais, Suzanne Spaan, Maria-Pilar Martinez-Moral, Kurunthachalam Kannan, Vincent W V Jaddoe, Stephanie M Engel, Anjoeka Pronk and 3 more

Abstract read
In one paragraph

Article in Molecular psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Phthalates Induced Neurotoxicity: A Mechanistic Approach.Central nervous system agents in medicinal chemistry · 2026
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Pandora's Box.BJPsych international · 2024
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Akhgar Ghassabian *Department of Pediatrics, New York University School of Medicine, New York, NY, USA.ORCID 0000-0001-9551-4706
Michiel van den Dries *Department of Child and Adolescent Psychiatry, Erasmus University Medical Center, Rotterdam, the Netherlands.
Leonardo TrasandeDepartment of Pediatrics, New York University School of Medicine, New York, NY, USA.
Sander LamballaisDepartment of Clinical Genetics, Erasmus University Medical Center, Rotterdam, the Netherlands.ORCID 0000-0003-3118-6330
Suzanne SpaanDepartment of Risk Analysis for Products in Development, TNO, Utrecht, the Netherlands.
Maria-Pilar Martinez-MoralOncology Area, Center for Biomedical Research of La Rioja, Logroño, Spain.ORCID 0000-0003-3927-8846
Kurunthachalam KannanDepartment of Pediatrics, New York University School of Medicine, New York, NY, USA.
Vincent W V JaddoeThe Generation R Study Group, Erasmus University Medical Center, Rotterdam, the Netherlands.ORCID 0000-0003-2939-0041
Stephanie M EngelDepartment of Epidemiology, Gilling School of Global Public Health, University of North Carolina Chapel Hill, Chapel Hill, NC, USA.
Anjoeka PronkDepartment of Risk Analysis for Products in Development, TNO, Utrecht, the Netherlands.
Tonya WhiteSection on Social and Cognitive Developmental Neuroscience, National Institute of Mental Health Bethesda, Bethesda, MD, USA.
Henning TiemeierThe Generation R Study Group, Erasmus University Medical Center, Rotterdam, the Netherlands. tiemeier@hsph.harvard.edu.ORCID 0000-0002-4395-1397
Mònica GuxensDepartment of Child and Adolescent Psychiatry, Erasmus University Medical Center, Rotterdam, the Netherlands.

Funding

UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Stephanie Engel · 2001 to 2026
$36.3M
Brain Influences of Phthalates and Bisphenols in AdolescentsR01ES032826 · NIEHS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Akhgar Ghassabian · 2021 to 2026
$2.8M
Prenatal Toxicant Exposure and Risk of Attention-Deficit Hyperactivity DisorderR01ES021777 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ENGEL, STEPHANIE · 2012 to 2016
$2.8M
Preconceptual Bisphenol and Phthalate Effects on Early Embryonic DevelopmentR01ES029779 · NIEHS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI TRASANDE, LEONARDO · 2018 to 2023
$2.7M
Phthalates, BPA, Trajectories of In and Ex Utero Growth and Cardiometabolic RisksR01ES022972 · NIEHS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI TRASANDE, LEONARDO · 2014 to 2018
$2.7M
NIEHS NIH HHS P30 ES010126NIEHS NIH HHS R01 ES021777NIEHS NIH HHS R01 ES022972NIEHS NIH HHS R01 ES029779NIEHS NIH HHS R01 ES032826
6 · The paper itself

Abstract

Exposure to phthalates, used as plasticizers and solvents in consumer products, is ubiquitous. Despite growing concerns regarding their neurotoxicity, brain differences associated with gestational exposure to phthalates are understudied. We included 775 mother-child pairs from Generation R, a population-based pediatric neuroimaging study with prenatal recruitment, who had data on maternal gestational phthalate levels and T

Indexed as

Phthalic AcidsPrenatal Exposure Delayed EffectsAdolescentChildFemaleGray MatterHumansLongitudinal StudiesMaternal ExposurePlasticizersPregnancyphthalic acidPhthalic AcidsPlasticizers

Identifiers

PMID37644173
PMCPMC11062447

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.