ArticleNPJ digital medicine2023
Systematic review and meta-analysis comparing educational and reminder digital interventions for promoting HPV vaccination uptake.
Article in NPJ digital medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Video-based interventions to promote HPV vaccination among individuals aged 9 to 26: a systematic review and meta-analysis.BMC public health · 2026Pooled it
- Digital tools to enhance adherence to cervical cancer prevention practices: systematic review.Frontiers in public health · 2026Pooled it
- Moderators of body composition change in response to sprint interval training versus moderate-intensity continuous training: a systematic review and meta-regression analysis.BMC public health · 2025Pooled it
- Are there differences in efficacy and safety between local and imported direct-acting antiviral agents for hepatitis C in China?Infectious diseases of poverty · 2025Pooled it
- Impact of measles vaccination strategies on vaccination rates in low-income and middle-income countries: a systematic review and meta-analysis.BMJ global health · 2025Pooled it
- Gender-neutral vs. gender-specific strategies in school-based HPV vaccination programs: a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- Electronic Health Interventions and Cervical Cancer Screening: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2024Pooled it
- Digital Intervention (MiVacunaLA 2.0) to Promote COVID-19 Vaccine Acceptance Among Hispanic Children: Community-Based Randomized Controlled Trial.Journal of medical Internet research · 2026Trial
- Short-term outcomes of health belief model-based brief virtual education on HPV infection and vaccination among pharmacy students: a randomized controlled trial.BMC medical education · 2026Trial
- Effects of an educational health promotion intervention to improve human papillomavirus vaccination acceptance and uptake among adolescent girls: a cluster randomized controlled trial.BMC public health · 2025Trial
- TeenVac.org: A Mobile Web App to Improve Human Papillomavirus Vaccine Uptake for Adolescent Boys.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2025Trial
- Randomized Controlled Trial of Impact of Mobile Health Technologies on Human Papillomavirus Vaccination Uptake in Mothers of Vaccine-Eligible Girls in Lagos, Nigeria (mHealth-HPVac).JCO global oncology · 2025Trial
- Trial
- Teacher communication style and adolescent human papillomavirus vaccination in Bangkok schools.AJOG global reports · 2026Article
- HPV vaccination hesitancy and acceptance among parents in Saxony-Anhalt, Germany: the role of gender, awareness and fear.BMC public health · 2025Article
- Article
- Article
- [Vaccination reminders in Germany: inventory and ideas for tomorrow using the example of HPV vaccination : Report on the results of the InveSt HPV project].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2025Review
- Trust in official information as a key predictor of COVID-19 vaccine acceptance: evidence from a Czech longitudinal survey study.BMC public health · 2025Article
- Exploring the role of the oncology nurse in cervical cancer screening programs during times of transition.Canadian oncology nursing journal = Revue canadienne de nursing oncologique · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Global Human papillomavirus (HPV) vaccination rates remain low despite available WHO-approved vaccines. Digital interventions for promoting vaccination uptake offer a scalable and accessible solution to this issue. Here we report a systematic review and meta-analysis examining the efficacy of digital interventions, comparing educational and reminder approaches, for promoting HPV vaccination uptake (HVU). This study also identifies factors influencing the effectiveness of these interventions. We searched PubMed, PsycInfo, Web of Science, and the Cochrane Library from each database's inception to January 2023. Three raters independently evaluate the studies using a systematic and blinded method for resolving disagreements. From 1929 references, 34 unique studies (281,280 unique participants) have sufficient data. Client reminder (OR, 1.41; 95% CI, 1.23-1.63; P < 0.001), provider reminder (OR, 1.39; 95% CI, 1.11-1.75; P = 0.005), provider education (OR, 1.18; 95% CI, 1.05-1.34; P = 0.007), and client education plus reminder interventions (OR, 1.29; 95% CI, 1.04-1.59; P = 0.007) increase HVU, whereas client education interventions do not (OR, 1.08; 95% CI, 0.92-1.28; P = 0.35). Digital intervention effectiveness varies based on participants' gender and the digital platform used. Interventions targeting male or mixed-gender participants demonstrate greater benefit, and reminder platforms (SMS, preference reminders, or electronic health record alerts) are more effective in increasing HVU. Digital interventions, particularly client and provider reminders, along with provider education, prove significantly more effective than client education alone. Incorporating digital interventions into healthcare systems can effectively promote HPV vaccination uptake. Reminder interventions should be prioritized for promoting HVU.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.