Evidence map›Paper›PMID 37644089›Full record

ArticleScientific reports2023

The effect of mycophenolate mofetil on podocytes in nephrotoxic serum nephritis.

A Hackl, E Nüsken, J Voggel, S E D Abo Zed, J Binz-Lotter, D Unnersjö-Jess, C Müller, G Fink, K Bohl, E Wiesner and 9 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. The CaPediatric nephrology (Berlin, Germany) · 2025
    Review
  4. Dissecting endothelial cell heterogeneity with new tools.Cell regeneration (London, England) · 2025
    Review
  5. Podocytes in health and glomerular disease.Frontiers in cell and developmental biology · 2025
    Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 3 institutions in 1 country.

A Hackl *Department of Pediatrics, Faculty of Medicine, University Hospital Cologne, University of Cologne, Kerpener Street 62, 50937, Cologne, Germany. agnes.hackl@uk-koeln.de.
E Nüsken *Department of Pediatrics, Faculty of Medicine, University Hospital Cologne, University of Cologne, Kerpener Street 62, 50937, Cologne, Germany.
J VoggelDepartment of Pediatrics, Faculty of Medicine, University Hospital Cologne, University of Cologne, Kerpener Street 62, 50937, Cologne, Germany.
S E D Abo ZedDepartment of Pediatrics, Faculty of Medicine, University Hospital Cologne, University of Cologne, Kerpener Street 62, 50937, Cologne, Germany.
J Binz-LotterCECAD, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.
D Unnersjö-JessCECAD, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.
C MüllerDepartment of Therapeutic Drug Monitoring, Pharmacology at the Laboratory Centre, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.
G FinkDepartment of Pediatrics, Faculty of Medicine, University Hospital Cologne, University of Cologne, Kerpener Street 62, 50937, Cologne, Germany.
K BohlCECAD, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.
E WiesnerCECAD, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.
P DiefenhardtCECAD, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.
C DafingerDepartment of Pediatrics, Faculty of Medicine, University Hospital Cologne, University of Cologne, Kerpener Street 62, 50937, Cologne, Germany.
H ChenCECAD, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.
M WohlfarthDepartment of Pediatrics, Faculty of Medicine, University Hospital Cologne, University of Cologne, Kerpener Street 62, 50937, Cologne, Germany.
R-U MüllerCECAD, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.
M J HacklCECAD, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.
B SchermerCECAD, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.
K-D NüskenDepartment of Pediatrics, Faculty of Medicine, University Hospital Cologne, University of Cologne, Kerpener Street 62, 50937, Cologne, Germany.
L T WeberDepartment of Pediatrics, Faculty of Medicine, University Hospital Cologne, University of Cologne, Kerpener Street 62, 50937, Cologne, Germany.
Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases · DEUniversity Hospital Cologne · DEUniversity of Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mycophenolate mofetil (MMF) is applied in proteinuric kidney diseases, but the exact mechanism of its effect on podocytes is still unknown. Our previous in vitro experiments suggested that MMF can ameliorate podocyte damage via restoration of the Ca

Indexed as

Mycophenolic AcidNephritisPodocytesActin CytoskeletonAnimalsKidney GlomerulusMiceMice, Inbred C57BLProteomeMycophenolic AcidProteome

Identifiers

PMID37644089
PMCPMC10465485
OpenAlexW4386250198

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.