Evidence map›Paper›PMID 37643866›Full record

ArticleLife science alliance2023

Grp78 is required for intestinal Kras-dependent glycolysis proliferation and adenomagenesis.

Claudia N Spaan, Ruben J de Boer, Wouter L Smit, Jonathan Hm van der Meer, Manon van Roest, Jacqueline Lm Vermeulen, Pim J Koelink, Marte Aj Becker, Simei Go, Joana Silva and 4 more

Open access · goldAbstract read
In one paragraph

Article in Life science alliance, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Claudia N SpaanDepartment of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
Ruben J de BoerDepartment of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands r.j.deboer@amsterdamumc.nl.ORCID https://orcid.org/0000-0001-6627-5136
Wouter L SmitDepartment of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
Jonathan Hm van der MeerDepartment of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
Manon van RoestDepartment of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
Jacqueline Lm VermeulenDepartment of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
Pim J KoelinkDepartment of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
Marte Aj BeckerDepartment of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
Simei GoDepartment of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
Joana SilvaDepartment of Oncogenomics, Netherlands Cancer Institute, Amsterdam, Netherlands.
William J FallerDepartment of Oncogenomics, Netherlands Cancer Institute, Amsterdam, Netherlands.ORCID https://orcid.org/0000-0002-0738-2254
Gijs R van den BrinkDepartment of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
Vanesa MuncanDepartment of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
Jarom HeijmansDepartment of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands j.heijmans@amsterdamumc.nl.ORCID https://orcid.org/0000-0001-9615-7851
Amsterdam University Medical Centers · NLThe Netherlands Cancer Institute · NLUniversity of Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In development of colorectal cancer, mutations in

Indexed as

Endoplasmic Reticulum Chaperone BiPAnimalsCell ProliferationGlucoseGlucose Transporter Type 1GlycolysisIntestinesMiceProto-Oncogene Proteins p21(ras)Endoplasmic Reticulum Chaperone BiPGlucoseGlucose Transporter Type 1Hras protein, mouseHspa5 protein, mouseProto-Oncogene Proteins p21(ras)

Identifiers

PMID37643866
PMCPMC10465924
OpenAlexW4386241917

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.