Evidence map›Paper›PMID 37643857›Full record

Trial reportBMJ open2023

Safety and efficacy of Vitamin D

Arkapal Bandyopadhyay, Sarika Palepu, Puneet Dhamija, Uttam Kumar Nath, Rituparna Chetia, Anamika Bakliwal, Sudeep Vaniyath, Debranjani Chattopadhyay, Shailendra Handu

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Emerging role of MYB transcription factors in cancer drug resistance.Cancer drug resistance (Alhambra, Calif.) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Arkapal BandyopadhyayDepartment of Pharmacology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.ORCID 0000-0001-9755-0233
Sarika PalepuCommunity Medicine and Family Medicine, All India Institute of Medical Sciences, Kalyani, West Bengal, India.ORCID 0000-0001-6534-2149
Puneet DhamijaDepartment of Pharmacology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.ORCID 0000-0002-2890-4939
Uttam Kumar NathDepartment of Medical Oncology Haematology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.ORCID 0000-0001-7762-803X
Rituparna ChetiaDepartment of Medical Oncology Haematology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Anamika BakliwalDepartment of Medical Oncology Haematology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Sudeep VaniyathDepartment of Medical Oncology Haematology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Debranjani ChattopadhyayDepartment of Medical Oncology Haematology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Shailendra HanduDepartment of Pharmacology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India shailendra.phar@aiimsrishikesh.edu.in.ORCID 0000-0002-4769-9176
All India Institute of Medical Sciences Rishikesh · INAll India Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe study aimed to compare early molecular response (EMR) rates at 3 months of imatinib therapy with and without vitamin D

designDouble-blind, placebo-controlled, exploratory randomised trial.

settingTertiary care hospital in northern India.

participantsTreatment-naive patients with chronic phase chronic myeloid leukaemia (n=62) aged >12 years were recruited from January 2020 to January 2021. Patients with progressive disease, pregnancy and hypercalcaemia were excluded.

interventionOral vitamin D PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome was to compare EMR (defined as

resultsAt baseline, 14.5% of the patients had normal vitamin D

conclusionVitamin D TRIAL REGISTRATION NUMBER: CTRI/2019/09/021164.

Indexed as

Leukemia, Myelogenous, Chronic, BCR-ABL PositiveCholecalciferolDietary SupplementsFemaleHumansImatinib MesylateIndiaPregnancyCholecalciferolImatinib Mesylateclinical pharmacologyclinical trialsleukaemiamolecular aspects

Identifiers

PMID37643857
PMCPMC10465917
OpenAlexW4386247197

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.