Evidence map›Paper›PMID 37643473›Full record

ArticleeLife2023

lncRNA read-through regulates the BX-C insulator

Airat Ibragimov, Xin Yang Bing, Yulii V Shidlovskii, Michael Levine, Pavel Georgiev, Paul Schedl

Abstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. eLife · 2024
    Article
  6. Molecular and genetic characterization ofmicroPublication biology · 2024
    Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Airat IbragimovDepartment of Molecular Biology, Princeton University, Princeton, United States.ORCID 0000-0002-5973-9147
Xin Yang BingLewis Sigler Institute, Princeton University, Princeton, United States.
Yulii V ShidlovskiiLaboratory of Gene Expression Regulation in Development, Institute of Gene Biology Russian Academy of Sciences, Moscow, Russian Federation.ORCID 0000-0002-3643-9889
Michael LevineLewis Sigler Institute, Princeton University, Princeton, United States.
Pavel GeorgievDepartment of the Control of Genetic Processes, Institute of Gene Biology Russian Academy of Sciences, Moscow, Russian Federation.
Paul SchedlDepartment of Molecular Biology, Princeton University, Princeton, United States.ORCID 0000-0001-5704-2349

Funding

Visualization of gene activity in the Drosophila embryoR35GM118147 · NIGMS · PRINCETON UNIVERSITY · PI Michael Steven Levine · 2016 to 2026
$6.7M
Genetic regulatory mechanism in development and differentiationR35GM126975 · NIGMS · PRINCETON UNIVERSITY · PI SCHEDL, PAUL D · 2018 to 2022
$3.0M
NIGMS NIH HHS R35 GM118147NIGMS NIH HHS R35 GM126975
6 · The paper itself

Abstract

Though long non-coding RNAs (lncRNAs) represent a substantial fraction of the Pol II transcripts in multicellular animals, only a few have known functions. Here we report that the blocking activity of the Bithorax complex (BX-C)

Indexed as

HypersensitivityRNA, Long NoncodingAnimalsPromoter Regions, GeneticRNA Polymerase IIRNA, Long NoncodingRNA Polymerase IIbithoraxchromatin boundarychromosomesCTCFdevelopmental biologyD. melanogasterFub-1gene expressioninsulatorlncRNA

Identifiers

PMID37643473
PMCPMC10497285

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.