Evidence map›Paper›PMID 37642935›Full record

ArticleMolecular neurobiology2024

Genetic Ablation of Dentate Hilar Somatostatin-Positive GABAergic Interneurons is Sufficient to Induce Cognitive Impairment.

Rajasekar Nagarajan, Jinrui Lyu, Maltesh Kambali, Muxiao Wang, Connor D Courtney, Catherine A Christian-Hinman, Uwe Rudolph

Open access · greenAbstract read
In one paragraph

Article in Molecular neurobiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Rajasekar NagarajanDepartment of Comparative Biosciences, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Jinrui LyuDepartment of Comparative Biosciences, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Maltesh KambaliDepartment of Comparative Biosciences, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Muxiao WangDepartment of Comparative Biosciences, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Connor D CourtneyNeuroscience Program, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Catherine A Christian-HinmanNeuroscience Program, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Uwe RudolphDepartment of Comparative Biosciences, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, IL, USA. urudolph@illinois.edu.ORCID http://orcid.org/0000-0001-9396-4746
University of Illinois Urbana-Champaign · US

Funding

Cellular mechanisms for age-related cognitive dysfunction and its pharmacological reversal: a strategy towards prevention and treatment of postoperative cognitive deficits in elderly patientsR01GM128183 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI RUDOLPH, UWE · 2019 to 2022
$1.6M
NIGMS NIH HHS R01 GM128183NIGMS NIH HHS R01GM128183
6 · The paper itself

Abstract

Aging is often associated with a decline in cognitive function. A reduction in the number of somatostatin-positive (SOM

Indexed as

Cognitive DysfunctionInterneuronsAnimalsHippocampusMiceNeuronsSomatostatinSomatostatinAgingDiphtheria toxinGABAergic interneuronsMicroglia

Identifiers

PMID37642935
PMCPMC11285310
OpenAlexW4386251169

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.