Evidence map›Paper›PMID 37642799›Full record

ArticleInternational ophthalmology2023

Distinguishing laboratory characteristics in giant cell arteritis: a real-world retrospective cohort study.

Raghav Goel, Eiman Usmani, Stephen Bacchi, Sumu Simon, Weng Onn Chan

Abstract read
In one paragraph

Article in International ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Raghav GoelRoyal Adelaide Hospital, Adelaide, SA, 5000, Australia.ORCID https://orcid.org/0000-0002-6875-578X
Eiman UsmaniRoyal Adelaide Hospital, Adelaide, SA, 5000, Australia. usmani.eiman@gmail.com.
Stephen BacchiRoyal Adelaide Hospital, Adelaide, SA, 5000, Australia.
Sumu SimonRoyal Adelaide Hospital, Adelaide, SA, 5000, Australia.
Weng Onn ChanRoyal Adelaide Hospital, Adelaide, SA, 5000, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUntreated Giant Cell Arteritis (GCA) has the potential to cause serious complications such as vision loss. Appropriate initial assessment by General Practitioners, early treatment and specialist referral are therefore essential in reducing morbidity. However, lack of awareness around the range of presentations can lead to a delay in diagnosis.

objectiveWe aim to evaluate the discriminative diagnostic performance of laboratory characteristics associated with GCA in our population over a period of 18 months. DISCUSSION: This is a real-world retrospective review of patients referred to ophthalmology services with concern for GCA. The pre-test probability of a patient referred with suspected GCA was 13.9% to have GCA, highlighting the need for specialist referrals to continue. White Cell Count (p = 0.01), Platelet Count (p = 0.02), Erythrocyte sedimentation rate (p = 0.004) and C-reactive protein (p = 0.002) were significantly different between GCA and non-GCA cases. Moreover, this study demonstrates that absolute neutrophil count (p = 0.02) can be a useful parameter in initial investigations for GCA.

Indexed as

Giant Cell ArteritisC-Reactive ProteinHumansLeukocyte CountRetrospective StudiesC-Reactive ProteinCRPESRGCAGCA suspectRetrospective study

Identifiers

PMID37642799
PMCPMC10520135

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Registered trials

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