Evidence map›Paper›PMID 37642748›Full record

ArticleEuropean journal of nutrition2023

Relationship between vitamin D, iron, and hepcidin in premenopausal females, potentially confounded by ethnicity.

Anya Greenwood, Pamela Ruth von Hurst, Kathryn Louise Beck, Hajar Mazahery, Kimberley Lim, Claire Evelyn Badenhorst

Abstract read
In one paragraph

Article in European journal of nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anya GreenwoodSchool of Sport, Exercise and Nutrition, Massey University Auckland, Auckland, New Zealand.
Pamela Ruth von HurstSchool of Sport, Exercise and Nutrition, Massey University Auckland, Auckland, New Zealand.ORCID http://orcid.org/0000-0001-6326-7501
Kathryn Louise BeckSchool of Sport, Exercise and Nutrition, Massey University Auckland, Auckland, New Zealand.ORCID http://orcid.org/0000-0003-1825-1927
Hajar MazaherySchool of Sport, Exercise and Nutrition, Massey University Auckland, Auckland, New Zealand.ORCID http://orcid.org/0000-0002-3743-2152
Kimberley LimSchool of Sport, Exercise and Nutrition, Massey University Auckland, Auckland, New Zealand.
Claire Evelyn BadenhorstSchool of Sport, Exercise and Nutrition, Massey University Auckland, Auckland, New Zealand. c.badenhorst@massey.ac.nz.ORCID http://orcid.org/0000-0002-8434-9730

Funding

Massey University Massey University Research Fund
6 · The paper itself

Abstract

purposeTo investigate the associations between vitamin D, hepcidin, and iron status in premenopausal females of different ethnic cohorts residing in Auckland, New Zealand (NZ).

methodsA total of 160 females aged 18-45 years participated in a cross-sectional study. Demographics, body composition, serum 25(OH)D, inflammatory markers (C-reactive protein and interleukin-6, IL-6), and iron biomarkers (serum ferritin, haemoglobin, soluble transferrin receptor, and hepcidin) were measured. Comparisons between parametric, non-parametric, and categorical variables were completed by using one-way ANOVA, Kruskal-Wallis, and Chi-squared tests, respectively. ANCOVA was used to compare serum 25(OH)D across iron parameter categories.

resultsOf the 160 participants, 60 were NZ European, 67 were South Asian, and 33 were from the 'other' ethnic groups. South Asians had significantly higher body fat percentage (BF%) and IL-6 concentration (38.34% and 1.66 pg·mL

conclusionWithin South Asian women, an unexpected positive relationship between 25(OH)D and hepcidin concentration was observed which may be due to significantly higher IL-6 concentrations, BF%, and lower 25(OH)D concentrations. Future research is required to confirm these observations in this ethnic cohort.

Indexed as

IronVitamin DAdolescentAdultCross-Sectional StudiesEthnicityFemaleFerritinsHepcidinsHumansInterleukin-6Middle AgedVitaminsYoung AdultFerritinsHepcidinsInterleukin-6IronVitamin DVitaminsIron regulationSerum 25(OH)DSerum ferritinSouth AsianVitamin D status

Identifiers

PMID37642748
PMCPMC10611866

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.