ArticlePediatric surgery international2023
Long-term bowel function after single-stage transanal endorectal pull-through in neonatal patients with Hirschsprung disease.
Article in Pediatric surgery international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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8 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.
- Does laparoscopic-assisted transanal endorectal pull-through improve outcomes compared with transanal endorectal pull-through in Hirschsprung disease? A systematic review and meta-analysis.Pediatric surgery international · 2026Pooled it
- Safety and feasibility of one-stage neonatal approach for short-segment Hirschsprung's disease.PloS one · 2026Article
- Features of defecation dysfunction among patients with Hirschsprung disease in early childhood.BMC gastroenterology · 2025Observational
- The association between short-term postoperative complications and bowel function after surgery for Hirschsprung disease.BMC pediatrics · 2025Article
- Risk factors and nomogram model for short-term postoperative complications in patients with hirschsprung disease.BMC medical informatics and decision making · 2025Article
- Bowel Function Score in Long-Term Follow-Up for Children with Hirschsprung Disease: OASIS-Holistic Care in Hirschsprung Disease Network Position Paper.Children (Basel, Switzerland) · 2024Article
- Clinical characteristics and influence of postoperative Hirschsprung-associated enterocolitis: retrospective study at a tertiary children's hospital.Pediatric surgery international · 2024Article
- Risk factors and simple scoring system for predicting postoperative nutritional status of Hirschsprung's disease.Frontiers in nutrition · 2024Article
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6 authors at 2 institutions in 1 country.
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Abstract
backgroundThe aim of this study was to assess long-term outcomes of neonatal patients with Hirschsprung disease (HD) after single-stage transanal endorectal pull-through (TEPT) and to explore the predictive factors contributing to subnormal bowel function.
methodsPatients aged > 3 years operated for HD with TEPT during neonatal period between 2007 and 2019 answered the bowel function score (BFS) questionnaire. The patients were retrospectively divided into two groups according to whether they had normal bowel function. The clinical variables were compared between the subnormal and normal BFS groups. Univariate and multivariable logistic regression analysis were performed to identify the predictive factors contributing to subnormal bowel function.
resultsA total of 160 children (71.7%) were included in this study, with mean follow-up time of 7.3 years (range 3.0-15.1 years). The level of aganglionosis were determined to be the short-segment (124/160, 77.5%), long-segment (33/160, 20.6%), and TCA (3/160, 1.9%). One hundred and thirty-four patients (83.8%) had a BFS ≥ 17, and 26 patients (16.2%) with subnormal bowel function (BFS < 17). Univariate and multivariate logistic regression analysis showed that level of aganglionosis with long-segment or TCA and postoperative hospital stay > 8.5 days were independent risk factors with OR of 3.213 (1.252, 8.246) and 3.813 (1.371, 10.606) for subnormal BFS, respectively.
conclusionMost HD patients who underwent one-stage TEPT in the neonatal period have favorable long-term results, and the level of aganglionosis with long-segment or TCA and long postoperative hospital stay may be closely related to subnormal bowel function.
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