Evidence map›Paper›PMID 37642712›Full record

SynthesisEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2023

Is adenotonsillectomy effective in improving central apnea events in patients with obstructive sleep apnea? A systematic review and meta-analysis.

Nasser Almutairi, Waleed Alshareef, Latifah Almakoshi, Abdulmajeed Zakzouk, Abdullah Aljasser, Ahmed Alammar

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Nasser AlmutairiDepartment of Otolaryngology-Head and Neck Surgery, King Saud University Medical City, P.O Box 245, 11411, Riyadh, Saudi Arabia. Dr.nasser-20@hotmail.com.ORCID http://orcid.org/0000-0003-4408-6531
Waleed AlshareefDepartment of Otolaryngology-Head and Neck Surgery, King Saud University Medical City, P.O Box 245, 11411, Riyadh, Saudi Arabia.
Latifah AlmakoshiDepartment of Otolaryngology-Head and Neck Surgery, King Saud University Medical City, P.O Box 245, 11411, Riyadh, Saudi Arabia.
Abdulmajeed ZakzoukDepartment of Otolaryngology-Head and Neck Surgery, King Saud University Medical City, P.O Box 245, 11411, Riyadh, Saudi Arabia.
Abdullah AljasserDepartment of Otolaryngology-Head and Neck Surgery, King Saud University Medical City, P.O Box 245, 11411, Riyadh, Saudi Arabia.
Ahmed AlammarDepartment of Otolaryngology-Head and Neck Surgery, King Saud University Medical City, P.O Box 245, 11411, Riyadh, Saudi Arabia.
King Saud Medical City · SAAlfaisal University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the effects of adenotonsillectomy on improving central sleep apnea events in children with obstructive sleep apnea (OSA).

methodsWe searched four online databases for relevant articles published from inception until October 2022. We included studies that measured the number of central apnea events per sleep and central apnea-hypopnea index (CAHI) or central apnea index (CAI) scores in children with OSA before and after adenotonsillectomy. Our primary outcomes were changes in CAI scores, the number of central apnea events per sleep, and CAHI scores after surgery. Our secondary outcomes were changes in total and mixed apnea events, improvement of sleep outcomes, and differences in oxygen or carbon dioxide saturation during sleep. We performed meta-analyses by pooling the mean changes of all included studies with a 95% confidence interval using Stata 17. Subsequently, we performed subgroup analyses based on the presence of comorbidities.

resultsWe included 22 studies comprising 1287 patients. Central and total sleep apnea parameters, except for CAHI and mixed apnea index scores, showed significant improvements after surgery. In addition, all respiratory parameters and second and third stages of non-rapid eye movement sleep showed significant postsurgical improvements. Patients with comorbidities showed significant improvements only in the total apnea-hypopnea index, oxygen desaturation index, and minimal oxygen saturation.

conclusionAdenotonsillectomy improves central apnea events in patients with OSA but not in those with comorbidities.

Indexed as

Sleep Apnea, CentralSleep Apnea, ObstructiveTonsillectomyAdenoidectomyChildHumansOxygenOxygenAdenoidectomyAdenotonsillectomyCentral apnea hypopneaCentral sleep apneaObstructive sleep apneaTonsillectomy

Identifiers

PMID37642712
OpenAlexW4386251998

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.