Evidence map›Paper›PMID 37642154›Full record

ArticleTransfusion2023

HIV risk behavior profiles among men who have sex with men interested in donating blood: Findings from the Assessing Donor Variability and New Concepts in Eligibility study.

Brian Custer, Barbee I Whitaker, Lance M Pollack, Renata Buccheri, Roberta L Bruhn, Lauren A Crowder, Susan L Stramer, Rita A Reik, Suchitra Pandey, Mars Stone and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Transfusion, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Brian CusterVitalant Research Institute, San Francisco, California, USA.ORCID 0000-0001-6251-366X
Barbee I WhitakerU.S. Food and Drug Administration, Center for Biologics Evaluation and Research, Silver Spring, Maryland, USA.ORCID 0000-0002-6311-6268
Lance M PollackDepartment of Laboratory Medicine, University of California San Francisco, San Francisco, California, USA.
Renata BuccheriVitalant Research Institute, San Francisco, California, USA.
Roberta L BruhnVitalant Research Institute, San Francisco, California, USA.ORCID 0000-0002-5898-8168
Lauren A CrowderAmerican Red Cross, Scientific Affairs, Rockville, Maryland, USA.ORCID 0000-0002-7261-1236
Susan L StramerAmerican Red Cross, Scientific Affairs, Gaithersburg, Maryland, USA.ORCID 0000-0002-5865-6366
Rita A ReikOneBlood, St. Petersburg, Florida, USA.
Suchitra PandeyStanford Blood Center & Stanford University, Palo Alto, California, USA.ORCID 0000-0003-3614-2353
Mars StoneVitalant Research Institute, San Francisco, California, USA.
Clara Di GermanioVitalant Research Institute, San Francisco, California, USA.ORCID 0000-0002-6047-211X
Kate BuchaczU.S. Centers for Disease Control and Prevention, HIV Research Branch, Division of HIV Prevention, Atlanta, Georgia, USA.
Anne F EderU.S. Food and Drug Administration, Center for Biologics Evaluation and Research, Silver Spring, Maryland, USA.ORCID 0000-0003-2328-626X
Yun LuU.S. Food and Drug Administration, Center for Biologics Evaluation and Research, Silver Spring, Maryland, USA.
Richard A ForsheeU.S. Food and Drug Administration, Center for Biologics Evaluation and Research, Silver Spring, Maryland, USA.
Steven A AndersonU.S. Food and Drug Administration, Center for Biologics Evaluation and Research, Silver Spring, Maryland, USA.
Peter W MarksU.S. Food and Drug Administration, Center for Biologics Evaluation and Research, Silver Spring, Maryland, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIndividual risk assessment allows donors to be evaluated based on their own behaviors. Study objectives were to assess human immunodeficiency virus (HIV) risk behaviors in men who have sex with men (MSM) and estimate the proportion of the study population who would not be deferred for higher risk HIV sexual behaviors. STUDY DESIGN AND

methodsCross-sectional survey and biomarker assessment were conducted in eight U.S. cities. Participants were sexually active MSM interested in blood donation aged 18-39 years, assigned male sex at birth. Participants completed surveys during two study visits to define eligibility, and self-reported sexual and HIV prevention behaviors. Blood was drawn at study visit 1 and tested for HIV and the presence of tenofovir, one of the drugs in oral HIV pre-exposure prophylaxis (PrEP). Associations were assessed between HIV infection status or HIV PrEP use and behaviors, including sex partners, new partners, and anal sex.

resultsA total of 1566 MSM completed the visit 1 questionnaire and blood draw and 1197 completed the visit 2 questionnaire. Among 1562 persons without HIV, 789 (50.4%) were not taking PrEP. Of those not taking PrEP, 66.2% reported one sexual partner or no anal sex and 69% reported no new sexual partners or no anal sex with a new partner in the past 3 months.

conclusionThe study found that questions were able to identify sexually active, HIV-negative MSM who report lower risk sexual behaviors. About a quarter of enrolled study participants would be potentially eligible blood donors using individual risk assessment questions.

Indexed as

Blood DonorsHIV InfectionsHomosexuality, MalePre-Exposure ProphylaxisRisk-TakingAdolescentAdultCross-Sectional StudiesHumansMaleSexual BehaviorSurveys and QuestionnairesYoung Adultdonorsregulatory and QAtransfusion-transmitted disease - HIV

Identifiers

PMID37642154
PMCPMC11284767

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.