Evidence map›Paper›PMID 37642052›Full record

ArticleAsian Pacific journal of cancer prevention : APJCP2023

Prognostic Role of Red Cell Distribution Width (RDW) in Patients with Diffuse Large B-cell Lymphoma.

Neda Kamandi, Amirmohammad Soleimanian, Abolghasem Allahyari, Mostafa Kamandi

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Article in Asian Pacific journal of cancer prevention : APJCP, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

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1 · What the graph read from it

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3 · Its place in the literature

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4 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  4. Red Cell Distribution Width in Diffuse Large B-cell Lymphoma.Asian Pacific journal of cancer prevention : APJCP · 2023
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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Neda KamandiFaculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Amirmohammad SoleimanianFaculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Abolghasem AllahyariDepartment of Hematology and Oncology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mostafa KamandiDepartment of Internal Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSeveral A number of prognostic blood markers related tofor Diffuse Large B-Cell Lymphoma (DLBCL) have been identified, most of which are costly and not easily availableaccessible. Although the relationship between the prognostic role of RDW and some cancers has been well established, the role it   of RDW plays in DLBCL patients is unclear still questionable and requires more investigations.

methodsAll patients diagnosed with DLBCL who had referred to Imam Reza Hospital, during  were included in this retrospective cohort study. Based onRegarding their RDW, the subjects were divided into two groups of normal (RDW ≤14.6%) and elevated RDW (RDW > 14.6%) RDW, and the outcomes were investigated.

resultsOne hundred fifty patients with DLBCL were included in this study. The results showed a significant relationship between the RDW values of the DLBCL patients and stage frequency distribution, relapse, mortality, and complete remission (P value<0.05). It was also found out that elevated RDW > 14.6% was associated with the risk of relapse (OR=2.50, P value<0.05), mortality (OR=3.59, P value<0.01), and lack of complete remission (OR=0.115, P value< 0.01). The results of the survival analysis indicated that the subjects with higher RDWs had a lower median survival rate than those with low RDWs. In addition, the mortality risk for the individuals with RDW > 14.6% was 2.44 times that of those with RDW≤14.6% (HR=2.44, P value<0.05).

conclusionThe results of this study well indicated that as an independent prognostic factor, RDW was associated with the stage of DLBCL patients, failure to achieve complete remission, disease relapse, and patient mortality. However, further studies are would be needed to realize determine the role of RDW in DLBCL patients.

Indexed as

Erythrocyte IndicesLymphoma, Large B-Cell, DiffuseClergyHumansPrognosisRetrospective StudiesDLBCLLymphomaPrognosisRed Cell Distribution Width factorsurvival

Identifiers

PMID37642052
PMCPMC10685207

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